Download RGUHS MBBS 2nd Year 2024 May 1026 Pathology Paper I Rs 4 Previous Question Paper

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Rajiv Gandhi University of Health Sciences, Karnataka

MBBS Phase - II (CBME) Degree Examination - 28-May-2024

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Time: Three Hours Max. Marks: 100 Marks

PATHOLOGY – PAPER I (RS-4)

Q.P. CODE: 1026

(QP contains two pages)

Your answers should be specific to the questions asked

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Draw neat, labeled diagrams wherever necessary

LONG ESSAYS 2 x 10 = 20 Marks

1. 40 year old farmer admitted to the hospital with high fever. He gives history of an injury to his left leg resulting in an ulcer 15 days ago. On examination his pulse is 110/min, blood pressure is 70/50 mmHg
   1. What is your diagnosis?
   2. Describe the stages of this condition
   3. Discuss the pathophysiology of the above condition

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2. 3 years old female child admitted to paediatric ward with long history of pallor and passing high coloured urine. There is a history of consanguineous marriage among parents. On examination child has pallor, stunted growth, icterus and enlarged spleen.
   1. What is your diagnosis?
   2. Describe the molecular pathogenesis of this condition
   3. Discuss the lab diagnosis of the above condition

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SHORT ESSAYS 8 x 5 = 40 Marks

3. Pathologic calcification
4. Arachidonic acid metabolites
5. Lepromatous leprosy
6. Type I hypersensitivity

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7. Mechanism of metastasis
8. Chronic myeloid leukemia
9. Von Willebrand's disease
10. Discuss phagocytosis

SHORT ANSWERS 10 x 3 = 30 Marks

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11. Name three endogenous pigments
12. Fate of primary tuberculosis
13. Advantages of FNAC
14. Fate of thrombus
15. Tumor markers

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16. Rickets
17. CSF findings in pyogenic meningitis
18. Stages of ESR
19. Coomb's test
20. Systemic causes for delayed wound healing

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Multiple Choice Questions 10 x 1 = 10 Marks

21. All of the following are special stains for fat EXCEPT
    1. Sudan dyes
    2. PAS
    3. Osmic acid

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    4. Oil Red O
22. 30 year old male on pure vegetarian diet presents with listlessness, tingling and numbness in his limbs. On lab evaluation his bone marrow shows presence of megaloblasts. Megaloblasts can be seen in
    1. Iron deficiency anaemia
    2. Haemolytic anaemia
    3. Vit B12 deficiency anemia

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    4. Hereditary Spherocytosis
23. The DNA Oncogenic virus implicated in cervical carcinogenesis is
    1. Human papilloma virus
    2. Herpes virus
    3. POX virus

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    4. Hepatitis B virus
24. Which of the following disease is X linked recessive inheritance
    1. Sickle cell anemia
    2. Adult polycystic kidney
    3. Haemophilia

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    4. Hereditary Spherocytosis
25. Which of the following is a tumor suppressor genes
    1. RB
    2. PDGF
    3. RAS

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    4. EGF

22. Delayed type of hypersensitivity resulting in the formation of a granuloma is typically seen in
    1. Type I hypersensitivity reaction
    2. Type II hypersensitivity reaction
    3. Type III hypersensitivity reaction

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    4. Type IV hypersensitivity reaction
23. Which of the following antibodies is likely to identified on laboratory testing in a patient with systemic lupus erythematosus
    1. Anti DS DNA
    2. SS-A
    3. SS-B

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    4. Jo-1
24. In cases of renal failure on long term hemodialysis which of following type of amyloid is seen
    1. Amyloid light chain (AL)
    2. Amyloid associated protein (AA)
    3. Amyloid beta 2 microglobulin (Abets2m)

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    4. Beta amyloid protein (A beta)
25. ESR is raised markedly in
    1. Multiple myeloma
    2. Malaria
    3. Acute myeloblastic leukemia

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    4. Haemophilia
26. Type of antibodies usually seen in chronic ITP are
    1. Ig A
    2. Ig M
    3. Ig E

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    4. Ig G

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