VNSGU BPT 2019 2nd Year 4003 Biochemistry theory and Pharmacology Question Paper

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RAN-4003

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Second Year B.Physiotherapy Examination
March / April - 2019
Biochemistry theory and Pharmacology

Instructions:

Fill up strictly the details on your answer book

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Name of the Examination: Second Year B.Physiotherapy Examination

Name of the Subject: Biochemistry theory and Pharmacology

Subject Code No.:

Student’s Signature

SECTION - 1

Q.1 Describe factors affecting enzyme activity and describe different types of enzyme inhibition in detail with examples. (10 Marks)

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OR

Q.1. Describe Glycolysis Pathway with its regulation and significance. (10 Marks)

Q.2. Write short notes. (Any three) (15 Marks)

1. Beta oxidation of the fatty acid.
2. Metabolic changes in diabetes mellitus

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3. Primary and secondary structure of Protein
4. Hemoglobin degradation and Describe jaundice

Q.3. Write short notes. (Any five) (15 Marks)

1. Explain: Mucopolysaccharides.
2. Justify: Frameshift mutation is more dangerous than point mutation.

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3. Justify: Ammonia is toxic to the brain.
4. Justify: Folic acid, vit.B12, and pyridoxine phosphate are used to reduce homocysteine level.
5. Justify: cAMP is considered as a second messenger.
6. Justify: Vit.D is Pro hormone.

SECTION - II

PHARMACOLOGY

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Q.1 Classify cholinergic drugs. Give the mechanism of action of anti-cholinesterase drugs & Give therapeutic uses of Anticholinergic Drugs. 10

OR

What is DRC, half-life, bioavailability & distribution. Give the process of absorption through the mucus membrane. 10

Q.2 Write Any Three 15

1. Nikorandil

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2. Organophosphorous Poisoning
3. Treatment of Myocardial Infarction
4. Macrolide Antibiotics.

Q.3 Write In Short - Any Five 15

1. What are bad factors of coronary artery? Give therapeutic uses of Ntg.

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2. Outline treatment of status asthmaticus.
3. Use of methacholine in diagnosis of pheochromocytoma.
4. Why ciprofloxacin is preferred in biliary infection
5. Give the mechanism of action of Methotrexate
6. What is the metabolism of Adrenaline.

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7. How will you assess the benefits of digitalis therapy?

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