Download OU Pharm D Question Paper 1st Year 2018 1103 Pharmaceutical Organic Chemistry

Download OU (Osmania University) Pharm D (Doctor of Pharmacy) 1st Year 2018 1103 Pharmaceutical Organic Chemistry Previous Question Paper

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OU - 1701 OU - 1701
Code No. 1103
FACULTY OF PHARMACY
Pharm. D (6 YDC) I-Year (Instant) Examination, March 2018
Subject : Pharmaceutical Organic Chemistry
Time : 3 Hours Max. Marks: 70
Note: Answer all questions from Part ? A, answer any five questions from Part-B.
PART ? A (10 x 2 = 20 Marks)
1 Define electrophile with examples.
2 Write the structural formula for the following:
(a) 2-ethyl -1-methyl butane
(b) 2 ? hydroxyl-4-pentanone
3 Define Baye?s strain theory.
4 Why chlorobenzene undergoes electrophonic?
5 Why acetic acid is stronger than ethanol?
6 Write the structure and medicinal uses of the following:
(a) Dimercaprol (b) Lactic acid
7 Why phenols are much more acidic than alcohols?
8 Write about Wittig Reaction.
9 Describe the various rules governing Resonance.
10 Define free radicals with examples.
PART ? B (5 x 10 = 50 Marks)
11 Define free radical substitution reaction. Explain the mechanism of halogenations of
alkanes.
12 Explain a note on E
1
and E
2
mechanism.
13 Explain the following:
(a) Markovinikov?s addition
(b) Free radical addition
14 Explain in detail about acyl substitution reaction with four examples.
15 Describe the mechanism and stereochemistry of S
N
1
reaction.
16 Write the reaction and mechanism of
(a) Cannizaro reaction
(b) Reformatsky reaction
17 Write the structure, preparation, assay and uses of the following:
(a) Asprin
(b) Saccharin sodium
18 Explain the following:
(a) Basicity of amines
(b) Benszoin condensation
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