Code No. 1110
FACULTY OF PHARMACY
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Pharm. D (6 YDC) II-Year (Instant) Examination, March 2018
Subject : Pharmacology - I
Time : 3 Hrs Max. Marks: 70
Note: Answer all questions from Part — A, answer any five questions from Part-B.
PART - A (10 x 2 = 20 Marks)
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- What is antagonism? Write the types of Antagonism with examples.
- What are Nasal decongestants? Give examples.
- Write one example each of Pharmacokinetic and Pharmacodynamic drug interactions.
- What is Plasma protein binding? Write its significance.
- What are Neuro muscular blockers? Write the mechanism of d-Tubocurarine.
- What are Tocolytics? Give examples.
- Write briefly on Oral contraceptives.
- What is Myasthenia gravis? Name the drugs used.
- Write the mechanism of action of Theophylline in bronchial asthma.
- Write the role of Angiotensin receptor blockers in hypertension.
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PART - B (5 x 10 = 50 Marks)
- Write the advantages and disadvantages of different routes of administration of drugs.
- Classify Anti-parkinsonism drugs. Write in detail about the drugs used to treat Parkinsonism.
- (a) Write short notes on CNS stimulants. (4)
(b) Write in detail about local anesthetics. (6) - (a) What is Eicosanoids? Write the biosynthesis. (4)
(b) Write pathophysiological role in Angiotensin and Prostaglandins. (6) - Write about : (a) G-protein coupled receptors (4)
(b) Different mechanism of Absorption of drugs (6) - Classify adrenergic blockers with examples. Write the pharmacology of (a) Prazosin (b) Propranolol
- What are Androgens? Write the physiological role of sex hormones.
- Classify Anti-arrhythmic drugs. Write in detail pharmacology of drugs used to treat Arrhythmias.
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