Code No. 4260
FACULTY OF PHARMACY
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Pharm. D (6 YDC) II-Year (Main) Examination, July 2017
Subject : Pharmacology-I
Time : 3 Hrs Max. Marks: 70
Note: Answer all questions from Part - A and answer any five questions from Part-B.
PART - A (10 x 2 = 20 Marks)
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- Explain the triple response of Histamine.
- Write the advantages of oral route of administration.
- Explain in brief about the types of Antagonism.
- Write the treatment for Parkinsonism.
- Write the classification of Bronchodilators.
- What is the pathophysiological role of 5-HT(5-Hydroxy tryptamine)?
- Write the adverse effects of Insulin.
- Explain the mechanism of action of local anaesthetics.
- Write the pharmacology of Nicotine.
- Explain about Biotransformation reaction in brief.
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PART -B (5 x 10 = 50 Marks)
- Explain the factors modifying drug action.
- Classify parasympathomimetics with examples. Write the mechanism of action, pharmacological actions and adverse effects of Acetyl choline.
- (a) Classify the drugs used in congestive Heart failure.
(b) Explain in detail about the pharmacological actions of any one drug with adverse effects in Diabetes mellitus. - (a) What are Anti-Histamines? Classify with examples. Write the pharmacological actions of any one drug.
(b) Write a note on 5-HT antagonists. - (a) What are opioid analgesics? Write the classification with examples.
(b) Write the pharmacological actions, adverse effects and therapeutic uses of paracetamol. - (a) Classify sedatives and hypnotics with examples.
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(b) Write a note on Anti-hyperlipedemic drugs. - (a) Explain Toxicity studies in detail.
(b) Write about the treatment of myasthenia gravis. - (a) Write the pharmacological actions of Insulin.
(b) Explain Drug-Drug Interactions with few examples.
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