Download OU Pharm D Question Paper 3rd Sem 2018 1113 Pharmacology II

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Code No. 1113

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FACULTY OF PHARMACY

Pharm. D (6 YDC) lll - Year (Instant) Examination, March 2018

Subject: Pharmacology - Il

Time: 3 Hrs Max. Marks: 70

Note: Answer all questions from Part - A and answer any five questions from Part-B.

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PART - A (10 x 2 = 20 Marks)

1. Write briefly abt Macromolecular assemblies.
2. Write note on Oncogenes.
3. Write note on Acute toxicity studies
4. Write the advantages of Azithromycin over the Macrolide antibiotics.

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5. Write the shared toxicities of Aminoglycoside
6. Explain briefly wobble Hypothesis.
7. Mention the complications of Loop diuretics.
8. Write the role of G-CSF and GN-CSF in Haemopoieses.
9. Write the adverse effects of Chloramphenicol.

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10. Write briefly the role of MAPK signaling pathways in Eukaryotic Cells.

PART - B (5 x 10 = 50 Marks)

11. Classify Antifungal drugs. Write the Pharmacology of Azoles.
12. Explain the process of transcription in Eukaryotes.
13. Explain the different phases of cell cycle and role of positive and negative regulators of cell cycle.

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14. (a) Explain the Pharmacology of Thiazida diuretics.
    (b) Write the mechanism of action, adverse effects and therapeutic uses of Sulfonamides.
15. (a) Classify anti cancer drugs. Write the pharmacology of Anti metabolites.
    (b) Write notes on Anti platelet drugs.
16. Explain in detail varis types of gene therapy with examples.

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17. Write the Pharmacology of Heparin and LMW heparins.
18. Write short notes on (i) Fluoroquinolones (ii) Tetracyclines