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FACULTY OF PHARMACY
Pharm D (6-YDC) V-Year (Instant) Examination, March 2018
Subject: Pharmacoepidemiology & Pharmacoeconomics
Time: 3 Hrs Max. Marks: 70
Note: Answer all questions from Part — A. Any Five questions from Part - B.
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PART - A (10x2 = 20 Marks)
- Write a note on the monetary units being used as an outcome measure.
- Write a brief note on time — risk relationship.
- Define morbidity.
- Write a brief note on incidence.
- Write a short note on case reports and its significance.
- Write the applications of pharmacoeconomics.
- Define serious adverse event.
- What is QALY?
- Define teratogenesis. Give two examples of teratogens.
- How are adverse effects with vaccines reported?
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PART - B (50 Marks)
- Elaborate on Cost Minimization analysis with a case study.
- a) Write in detail about adhoc data base systems.
b) Special issues in vaccine safety. - a) What are the various types of outcomes in pharmacoeconomic evaluations?
b) Write a note on the aims and potential applications of Pharmacoepidemiology. - a) Discuss in detail the various methods of measuring adherence.
b) Write in detail about relative risk and odds ratio. - a) Write a note on the strengths and weaknesses of spontaneous reporting system.
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b) Role of a pharmacist in formulary decision making. - a) Write in detail regarding the cohort studies, their strengths and weaknesses.
b) Explain prescription event monitoring and its use in pharmacoepidemiology. - a) Write briefly about meta -analysis and their role in PE studies.
b) What are the methodological issues to be addressed by pharmacoepidemiologic research in the studies on birth defects? - a) What are the various methods to measure utility?
b) Write a short note on ICER.
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