GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER- V EXAMINATION - SUMMER 2020
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Subject Code: 2150305 Date: 27/10/2020
Subject Name: MODELLING & SIMULATION OF PHYSIOLOGICAL SYSTEMS
Time: 02:30 PM TO 05:00 PM
Instructions:
- Attempt all questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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Q.1
(a) List the applications of physiological modelling. [03]
(b) Discuss the dissimilarities of physiological control system with engineering control system. [04]
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(c) Explain the oculomotor muscle model with appropriate diagrams. [07]
Q.2
(a) Draw the cardiac output and venous return curves. [03]
(b) Derive mathematical formulas of linear model of muscle mechanics. [04]
(c) Draw and explain the black box model of neuromuscular stretch reflex with necessary equations and result graphs. [07]
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OR
(c) Draw and explain the graphs of steady-state response of muscle stretch reflex. [07]
Q.3
(a) Draw & analyze the steady-state‘response of Glucose-Insulin model. [03]
(b) Equate mathematical formulas of gas exchange model. [04]
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(c) Draw and analyze the graphs showing steady-state of respiratory control mechanics. [07]
OR
(a) Draw & analyze the time domain response of Glucose-Insulin model. [03]
(b) “The negative feedback in physiological control system is embedded within the characteristics of the system.” Justify the statement with appropriate example. [07]
Q.4
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(a) Discuss the process of modelling with characteristics of good model. [03]
(b) List advantages of distributed parameter model with appropriate application. [04]
(c) Discuss various descriptive response of muscle mechanics model in terms of time domain characteristics. [07]
OR
(a) List advantages of lumped parameter model with appropriate application. [03]
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(b) Draw the strength-duration curve for a neuron. What part does the electrical resistance of membrane performs? [04]
(c) Draw and differentiate the steady-state graphs of single and double feedback loop of cardio vascular variability model. [07]
Q.5
(a) Define mean circulatory pressure with necessary equations. [03]
(b) Derive mathematical representation of venous return using mean circulatory pressure. [04]
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(c) Derive the mathematical formulas of time to Peak Overshoot and maximum velocity for Westheimer’s saccadic eye movement model. [07]
OR
(a) List out the assumptions made by Westheimer for developing saccadic eye movement model. [03]
(b) Draw and explain the Westheimer’s saccadic eye movement model with the transfer function. [04]
(c) Explain the model of respiratory sinus arrhythmia with necessary graphs. [07]
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