GTU B.Tech 2020 Winter Question Papers || Gujarat Technological University
Subject Code: 2260004 Date: 11/01/2021
Subject Name: Pharmaceutical Chemistry — VIII (Medicinal Chemistry — II)
Time: 2:00 PM TO 4:00 PM Total Marks: 54
Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
--- Content provided by FirstRanker.com ---
B.Ph- SEMESTER-VI EXAMINATION - WINTER-2020Subject Code: 2260004 Date: 11/01/2021
Subject Name: Pharmaceutical Chemistry — VIII (Medicinal Chemistry — II)
Time: 2:00 PM TO 4:00 PM Total Marks: 54
Instructions:
--- Content provided by FirstRanker.com ---
- Attempt any THREE questions from Q-1 to Q-6.
- Q.7 is compulsory to attempt.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
| Q.1 | (a) Define and classify general anesthetics with example. Explain Structure activity relationship of Benzodiazepines. | 06 |
| (b) Explain Structure activity relationship and mode of action of Tricyclic antidepressants. | 05 | |
| (c) Give synthesis of L-Dopa and Amphetamine. | 05 | |
| Q.2 | (a) Explain different theory of drug-receptor interactions in detail. | 06 |
| (b) Write a brief note on factors affecting drug- receptor interaction. | 05 | |
| (c) Define Xenobiotics. Give importance of CYP-450 in drug metabolism | 05 | |
| Q.3 | (a) What is a CNS stimulant? Explain classification of CNS stimulants with suitable example. Write a brief note on hallucinogenic agents. | 06 |
| (b) What is Parkinson’s disease? Write a note on antiparkinson’s agents. | 05 | |
| (c) Give synthesis of Halothane and Lignocaine. | 05 | |
| Q.4 | (a) Define and classify local anesthetics. Explain the SAR of Barbiturates. | 06 |
| (b) Write a brief note on factors affecting drug metabolism. | 05 | |
| (c) Give synthesis of Thiopental sodium and Phenobarbitone. | 05 | |
| Q.5 | (a) What is psychosis? Explain briefly about SAR for Phenothiazines. | 06 |
| (b) Write a brief note-on antigout agents. | 05 | |
| (c) Give synthesis of Fluoxetine and Imipramine. | 05 | |
| Q.6 | (a) Explain Various forces involved in drug-receptor interaction. | 06 |
| (b) Explain briefly about SAR for Local anesthetic agents. | 05 | |
| (c) Give synthesis of Chlordiazepoxide and Phenytoin. | 05 | |
| Q.7 | (a) Write a brief note on Phase-I and Phase-II metabolism in detail. --- Content provided by FirstRanker.com --- ORWrite a brief note on Cognition enhancers. | 06 |
| (a) Write synthesis of Mefenamic acid and Nimesulide. | 06 |
This download link is referred from the post: GTU B.Tech 2020 Winter Question Papers || Gujarat Technological University
--- Content provided by FirstRanker.com ---