Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.Pharm - SEMESTER- IV EXAMINATION — WINTER-2020
Subject Code: BP404TP Date: 12/02/2021
Subject Name: Pharmacology-I
Time: 02:30PM TO 04:30PM Total Marks: 54
Instructions:
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- Attempt any THREE questions from Q-1 to Q-6.
- Q.7 is compulsory to attempt.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Classify general anesthetics. Discuss various stages of general anesthesia. 06
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(b) Compare and contrast succinylcholine and d-tubocurarine as skeletal muscle relaxants. 05
(c) Differentiate Oral route and Parenteral route. 05
Q.2 (a) Classify anti-parkinsonian drugs. Describe pharmacology of levodopa combination with carbidopa. 06
(b) Describe Pharmacokinetic type of drug-drug interactions. 05
(c) Explain Pharmacological actions of alcohol. 05
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Q.3 (a) Discuss 1) Plasma protein binding 2) BBB. 06
(b) Describe mechanism of action and uses of lidocaine. 05
(c) Write a note on Organophosphorus poisoning and its treatment. 05
Q.4 (a) Explain signal transduction-mechanism of GPCR. 06
(b) Describe Rawlins Thompson classification of ADR in details. 05
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(c) Classify parasympatholytics. Discuss therapeutic uses of atropine. 05
Q.5 (a) Classify sympathomimetics. Describe Dale’s vasomotor reversal in detail. 06
(b) Enlist and Explain four phases of clinical trials. 05
(c) Differentiate competitive and non competitive antagonism. 05
Q.6 (a) Explain Phase I reactions of drug metabolism. 06
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(b) Discuss pharmacological actions and therapeutic uses of morphine. 05
(c) Write note on GABA as an inhibitory neurotransmitter of CNS. 05
Q.7 (a) Classify anti-depressants. Write a note on SSRIs. 06
OR
(a) Discuss Pharmacology of Phenytoin. 06
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OR
(a) Write a note on Pharmacovigilance. 06
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