Download GTU B.Pharma 2020 Summer 4th Sem BP403TP Physical Pharmaceutics Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 4th Sem BP403TP Physical Pharmaceutics Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B. PHARM SEMESTER ? IV EXAMINATION ? SUMMER 2020
Subject Code:BP403TP
Date: 28-10-2020
Subject Name: PHYSICAL PHARMACEUTICS - II
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Enlist methods for determination of particle size & explain coulter counter 06
method in detail with neat sketch.

(b) Explain two methods in determining particle surface area in detail with 05
necessary equations.

(c) Give factors affecting powder flow and methods to improve powder flow.
05



Q.2 (a) Classify various viscometers. Describe two viscometers with diagram to find 06
out viscosity of Non-Newtonian fluids.

(b) What is thixotropy and antithixotropy? Draw different types of thixotropic and 05
antithixotropy curves & explain the mechanism for their behavior with
examples.

(c) Define Viscosity. Describe Newtonian and non Newtonian system.
05



Q.3 (a) Explain the theory of Compaction & compression.
06

(b) Describe the Kawakita and Heckle equations in regard to compression.
05

(c) Explain Angle of repose, Carr's Index and Hausner ratio with their 05
pharmacopoeial specification.



Q.4 (a) Enumerate Properties of Colloids. Explain Kinetic Properties.
06

(b) Explain Purification method of colloidal solutions.
05

(c) Explain Applications of colloidal solutions.
05



Q.5 (a) What is second order kinetics? Derive equation with half life and shelf life for 06
second order kinetics?

(b) How to determination of reaction order? Explain it.
05

(c) What is first order kinetics? Derive equation with half life and shelf life?
05



Q. 6 (a) Define emulsion. Explain different theories of emulsion.
06

(b) Differentiate flocculated and deflocculated suspension.
05

(c) Define Surfactant. Give the different formula for calculation of HLB value.
05



Q.7 (a) What is suspension? Explain interfacial properties of suspended particles.
06

(b) Explain identification test for emulsion.
05

(c) Explain accelerated stability testing in expiration dating of pharmaceutical 05
dosage forms.
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