Download GTU B.Pharma 2020 Summer 6th Sem 2260003 Pharmaceutical Analysis Iv Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 6th Sem 2260003 Pharmaceutical Analysis Iv Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 6 EXAMINATION ? SUMMER -2020
Subject Code: 2260003
Date:28-10-2020
Subject Name: Pharmaceutical Analysis IV
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain principle, instrumentation and application of HPLC.
06

(b) Write in detail on detectors of HPLC.
05

(c) Differentiate between: i) HPLC & HPTLC, ii) HPLC & GC
05



Q.2 (a) Write note on LC-MS.
06

(b) Discuss various parameters of analytical method validation.
05

(c) Write a short note on supercritical fluid chromatography.
05



Q.3 (a) Explain principle, advantage, limitation and application of HPTLC.
06

(b) Explain following terms: (Any five)
05
(a) Retention time (b) Retention Volume (c) Resolution (d) Dead time (e)
HETP (f) Capacity factor (G) Asymmetric factor

(c) Write a note on Size exclusion chromatography.
05
Q.4 (a) Discuss about GLP
06

(b) What is Nuclear Chemistry? Write a note on Neutron Activation Analysis.
05

(c) Differentiate Raman spectroscopy and IR spectroscopy. Write a note on Raman 05
spectroscopy.



Q.5 (a) Enlist the detectors used in GC and discuss construction, working, advantages 06
and disadvantages of catherometer & FID.

(b) Describe derivatization in GC.
05

(c) Write a note on temperature programming in GC.
05



Q. 6 (a) Write a brief note on nephelometry.
06

(b) Write a note on GATT & TRIPS.
05

(c) Explain the steps involved in filing patent.
05



Q.7 (a) Write a note on ELISA.
06

(b) Write short note on RIA.
05

(c) Write a note on ISO9001:2000.
05
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