Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 6th Sem 2260004 Pharmaceutical Chemistry Viii (Medicinal Chemistry Ii) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 6 EXAMINATION ? SUMMER -2020
Subject Code: 2260004
Date:29-10-2020
Subject Name: Pharmaceutical Chemistry ? VIII (Medicinal Chemistry - II)
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a)
Give types of receptors. Discuss theories of drug receptor interaction in detail
06
(b)
What is CYP450 ? Explain its importance
05
(c)
Discuss factors affecting drug metabolism
05
Q.2 (a)
Discuss in detail the SAR of tricyclic antidepressants
06
(b)
Outline synthetic route for Amphetamine and Chlorpromazine
05
(c)
Explain importance of drug metabolism in drug design
05
Q.3 (a)
What are xenobiotics? How drugs metabolized in Phase-I metabolism
06
(b)
Discuss conjugation as mechanism of metabolism
05
(c)
What are cognition enhancers? Describe them in detail
05
Q.4 (a) Give an account of antiparkinsons agents. Give synthesis of L-Dopa
06
(b)
What is alzheimer disease?Discuss its treatment
05
(c)
What are the current developments in drugs acting on CNS?
05
Q.5 (a)
Give synthesis of any two : Paracetamol, Diclofenac and Nimesulide
06
(b)
Give an account of anti-gout agents
05
(c)
Explain terms NSAID and DMARD. How opioid analgesic differ from NSAID 05
Q. 6 (a) What are hypnotics and sedatives? What are anxiolytics? What are antipsychotics? 06
(b)
What are antiepileptics? Write a note on Hydantoins
05
(c)
Give an account of general and local anesthetics
05
Q.7 (a)
Classify antidepressants.Give name and structure of any one drug in each class
06
(b)
Write a note on Hallucinogens
05
(c)
Write a note on Barbiturates
05
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This post was last modified on 04 March 2021