Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 6th Sem BP601TP Medicinal Chemistry Iii Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 6 EXAMINATION ? SUMMER -2020
Subject Code: BP601TP Date:26-10-2020
Subject Name: Medicinal Chemistry III
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. All question carry marks.
Q.1 (a)
Discuss various approaches used in drug design.
6
(b)
Write brief note on Combinatorial Chemistry.
5
(c)
What is QSAR? Give detailed note on Hansch model.
5
Q.2 (a)
Classify Antimalarial Agents with examples and structures.
6
(b)
Discuss SAR of Quinolines.
5
(c)
Write note on concept and applications of Prodrugs.
5
Q.3 (a)
Differentiate terms with examples: Bacteriostatics & Bactericidals. Write
6
SAR of Cephalosporins.
(b)
Write short note on Chemistry of Aminoglycosides.
5
(c)
Discuss Chemistry and advantages of Semisynthetic Penicilins.
5
Q.4 (a)
Comment on: "Tetracyclines should not be taken with milk". Write SAR of
6
Tetracyclines.
(b)
Give synthesis of Chloramphenicol and Chloroquine
5
(c)
Write short note on Macrolides.
5
Q.5 (a)
What is MDR TB & XDR TB? Write a note on first-line Anti TB drugs.
6
(b)
Give synthesis of Isoniazid and Ciprofloxacin.
5
(c)
Write short note on Quinolones.
5
Q.6 (a)
Explain in brief about Azoles as Antifungal Agents. Write synthesis of
6
Tolnaftate.
(b)
Explain SAR of Sulphonamides. Write synthesis of Sulphamethoxazole.
5
(c)
Give the IUPAC name, synthesis and mechanism of Albendazole OR
5
Mebendazole, an anthelmintic agent.
Q.7 (a)
Write brief account on Antiamoebic Agents. Give synthesis of
6
Metronidazole.
(b)
Give synthesis of Trimethoprim and Nitrofurantoin
5
(c)
Write detailed note on Antiviral Agents.
5
*********************
This post was last modified on 04 March 2021