Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.PHARM - SEMESTER- 6 EXAMINATION - SUMMER -2020Subject Code:BP602TP Date: 27-10-2020
Subject Name: PHARMACOLOGY III
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
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- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Write mechanism of action, side effects of 1) Nelfinavir 2) Isoniazid 3) Tamoxifen. 06
(b) What is HAART? Write a note on drugs used in treatment of HIV infection. 05
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(c) Classify antifungal agents & write a note on azoles as antifungal agent. 05Q.2 (a) Classify third generation Cephalosporin’s & write its MOA and therapeutic actions. 06
(b) What is drug resistance? Write different mechanisms of transfer of resistance genes within and among bacteria. 05
(c) Explain the following terms : i) Acute toxicity ii) Superinfection iii) Jarish Herxheimer reaction iv) Cross resistance v) Kernicterus 05
Q.3 (a) Classify types of Leprosy. Write detail pharmacology of Dapsone. 06
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(b) Explain in brief tissue schizontocidal agents. 05(c) Explain in detail MDR-TB and write a note on DOTS. 05
Q.4 (a) Classify Laxatives. Explain Osmotic purgatives. 06
(b) Write MOA of following drugs: i) Metoclopramide ii) Mesalazine iii) Etofamide iv) Foscarnet v) Doxorubicin 05
(c) Write a note on anthelmintics. 05
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Q.5 (a) Write a note immunostimulants. 06
(b) Discuss the role of antimetabolites in treatment of cancer. 05
(c) Discuss treatment and management of diarrhea with emphasis on ORT. 05
Q.6 (a) Write in detail the drugs used in treatment of Syphilis and Gonorrhea. 06
(b) Classify the drugs used in treatment of UTI. Write a note on Quinolones. 05
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(c) Explain in brief the mechanism of biological agents as immunosuppressants. 05Q.7 (a) Explain the use of Leukotriene antagonists in treatment of asthma. 06
(b) Define cough. Differentiate between Expectorants and Antitussive agents 05
(c) Explain the role of chronology in occurrence of various diseases. 05
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