Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.PHARM - SEMESTER- 6 EXAMINATION - SUMMER -2020
Subject Code: BP60STP Date: 02-11-2020
Subject Name: Industrial Pharmacy — I
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
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- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Define Preformulation studies. Explain steps involved in Preformulation studies. (06)
(b) Describe in detail quality control for pharmaceutical aerosol products. (05)
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(c) Write a detail note on: 1. Parenteral suspension 2. Cryoprotectants (05)
Q.2 (a) What are pyrogens? Explain the sources of pyrogens in parenterals. Discuss principle and method of LAL test. (06)
(b) What are sunscreen preparations? Discuss their formulation and evaluation in brief. (05)
(c) Write a brief note on stability aspects of packing. (05)
Q.3 (a) Comment: Sedimentation rate of flocculated suspensions is faster than deflocculated suspensions. Differentiate flocculated and deflocculated suspension. (06)
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(b) Discuss defects observed in tablet compression process. (05)
(c) Explain quality control tests of gelatin. (05)
Q.4 (a) Enlist various container uses for Aerosol. Explain various types of actuator and valve used in aerosol. (06)
(b) Discuss in brief Pharmacopoeial tests for tablet. (05)
(c) Discuss remedies to overcome degradation due to hydrolysis and oxidation in pharmaceutical dosage-form. (05)
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Q.5 (a) What are various instabilities of emulsions? Discuss them with their causes and precautions to avoid them (06)
(b) Explain BCS classification of Drugs and its significance in Preformulation studies with suitable examples. (05)
(c) Write in brief note on formulation of ophthalmic dosage form. (05)
Q.6 (a) Classify cosmetics. Write short note on formulation, manufacturing and evaluation of shampoos (06)
(b) Discuss different film coating defects. (05)
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(c) Write a note on excipients and additives used in the capsule formulation (05)
Q.7 (a) Describe different types of glass as a packaging material for parenteral. Explain water attack test. (06)
(b) What is Pelletization? Discuss any one pelletization technique. (05)
(c) Write a detailed note on storage and purity of W.F.I. (05)
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