Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 3rd Sem 2230004 Pharmaceutical Chemistry Iv (Organic Chemistry I) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 3 EXAMINATION ? SUMMER -2020
Subject Code: 2230004
Date:29-10-2020
Subject Name: Pharmaceutical Chemistry-IV (Organic Chemistry ? I)
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Define hybridization. Explain hybrid orbitals with examples.
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(b) Write a note on Molecular Orbital Theory. Differentiate bonding and
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antibonding orbitals.
(c) Explain electronegativity and polarity of bonds.
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Q.2 (a) Comment on following:
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(i) Trichloroacetic acid is less acidic than acetic acid.
(ii) Cyclopentadiene is aromatic.
(iii) Dehydration of tertiary alcohol is faster than primary alcohol.
(b) Write a note on hydrogen bond.
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(c) Write a note on hyperconjugation and resonance.
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Q.3 (a) Explain in brief factors affecting organic reactions.
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(b) Give applications of carbenes and nitrenes.
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(c) Write note on reaction of dienes.
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Q.4 (a) Explain preparation and reaction of Grignard reagent.
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(b) Explain synthesis & reaction mechanism on Aldol Condensation.
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(c) General methods of preparations of Alkyl halides.
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Q.5 (a) Differentiate: SN1 and SN2 reactions.
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(b) Explain Hydroboration ? oxidation reaction of alkene with detailed mechanism. 05
(c) General methods of preparations of Alcohols.
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Q. 6 (a) Differentiate: E2 and E1 mechanism of elimination.
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(b) Give any three methods of preparations of Naphthalene.
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(c) Write a note on Williamson's synthesis of ether.
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Q.7 (a) Write reaction with mechanism of nitration of benzene.
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(b) What are Friedel craft reactions? Enlist its limitations.
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(c) Nitration of nitrobenzene yield m-dinitrobenzene: Justify.
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This post was last modified on 04 March 2021