Seat No.:
Enrolment No.
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GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 1 EXAMINATION - WINTER -2019
Subject Code: 2210002 Date: 30-12-2019
Subject Name: Pharm Chem-I (Inorganic Chemistry)
Time: 10:30 AM TO 01:30 PM Total Marks: 80
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1
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- (a) Define the following terms with examples. 06
- Astringent
- Emetic
- Laxative
- Sedative
- Expectorant
- Antioxidant.
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- (b) Enlist the sources of impurity in pharmaceuticals and explain the manufacturing hazards as source of impurity. 05
- (c) Write a note on Gutzeit test. 05
Q.2
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- (a) Write the assay principle of following compounds. 06
- Hydrogen peroxide
- Ammonium chloride
- Magnesium sulphate.
- (b) Define and classify antacids. Enumerate ideal characteristics of antacid. 05
- (c) Write a note on anaesthetics and respiratory stimulants. 05
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Q.3
- (a) Write the synonyms and uses of following compounds. 06
- Laughing gas
- Precipitated chalk
- Rochelle salt
- Caustic soda
- Lunar caustic
- Green vitriol.
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- (b) Define and Classify topical agents giving examples. 05
- (c) Give a brief note on chelating agents used in therapy. 05
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Q.4
- (a) Explain following terms. (Any three) 06
- Pharmacopoeia
- Limit test
- Assay
- Pharmaceutical aids
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- (b) Define and Classify antidotes giving examples. 05
- (c) Write briefly about various types of cathartics. 05
Q.5
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- (a) Write the synonyms and uses of following compounds. 06
- Epsom salt
- Bleaching powder
- Baking soda
- Slaked lime
- Boric acid
- Milk of magnesia.
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- (b) Classify dental products with suitable examples. Give a brief account of zinc chloride as a dental product. 05
- (c) Write in detail about types of water. 05
Q.6
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- (a) Write the assay principle of following compounds. 06
- Copper sulphate
- Calcium gluconate
- Borax.
- (b) Explain various mechanisms of inorganic antimicrobial agents with examples. 05
- (c) What are Radiopharmaceuticals? Give the application of Radiopharmaceuticals. 05
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Q.7
- (a) What are intra and extra cellular electrolytes? Write the physiological function of calcium and disease associated with it. 06
- (b) Define buffer and buffer capacity. Derive Handerson-Hasselbach equation for buffer action. 05
- (c) Justify the importance of 05
- Glycerine in assay of boric acid
- Citric acid in limit test for iron.
- Potassium iodide in aqueous iodine solution.
- Nitrobenzene in assay of ammonium chloride
- Hydrogen sulphide in limit test for heavy metal.
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