Seat No.:
Subject Code: 2230004
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 3 EXAMINATION - WINTER -2019
Subject Name: Pharmaceutical Chemistry-IV (Organic Chemistry —I)
Time: 10:30AM TO 01:30PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) Explain Different types of bond with example of each one. (06)
- (b) Define Carbocation. Write down the generation and reactions of Carbocation. (05)
- (c) Write a note on electronegativity and Polarity. (05)
- (a) Discuss in detail how Grignard reagent is helpful for synthesis of alcohol and alkanes. (06)
- (b) Write a descriptive note on Molecular Orbital Theory. (05)
- (c) How will you distinguish between primary, secondary and tertiary alcohol. (05)
- (a) Explain the Principle of Dumas Method and Kjeldahl method. (06)
- (b) Define Hybridization. Explain sp3 hybridization in detail. (05)
- (c) Discuss the chemical preparation and reactions of ether. (05)
- (a) Discuss the Haworth Synthesis of Anthracene. (06)
- (b) Explain halogenation of methane with its mechanism. (05)
- (c) Give two methods of preparation of alkene and alkyl halide. (05)
- (a) Give detailed notes on Aldol Condensation reaction with its mechanism. (06)
- (b) Write short note on Resonance. (05)
- (c) Write down in detail on Friedal Craft alkylation reaction in detail. (05)
- (a) Write a note on determination of molecular weight of volatile substances. (06)
- (b) Discuss quantitative analysis of Nitrogen element. (05)
- (c) State Saytzeff’s orientation and Kharash Peroxide effect with examples. (05)
- (a) Write down the methods of preparation and reactions of Diene. (06)
- (b) Write a note on Bonding and Anti-bonding orbitals. (05)
- (c) Explain the Intermolecular and Intramolecular forces. (05)
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Total Marks: 80
Date: 25-11-2019
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