Seat No.:
Subject Code: BP302TP
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 3 EXAMINATION - WINTER -2019
Subject Name: Physical Pharmaceutics I
Time: 10:30AM TO 01:30PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 | (a) Define solubility. Explain the factors affecting on solubility of drug with suitable example. | 06 |
(b) Discuss in detail Raoult’s low and its deviations. | 05 | |
(c) Write a note on distribution law with its limitations and applications. | 05 | |
Q.2 | (a) Explain in brief (1) Eutectic mixture (2) Sublimation. | 06 |
(b) Write a note on liquid crystals. | 05 | |
(c) Define refractive index. Explain the method used to determine refractive index. | 05 | |
Q.3 | (a) Enlist the methods used to measure the surface and interfacial tensions. Explain any one in detail. | 06 |
(b) Write a note on HLB scale. | 05 | |
(c) Explain in detail about surface active-agents. | 05 | |
Q.4 | (a) Define and classify the complexation. Write in detail about “chelates” | 06 |
(b) Describe the applications of complexation in field of pharmacy. | 05 | |
(c) Write a note on Protein drug binding kinetics. | 05 | |
Q.5 | (a) Enlist the methods used to determine the pH. Discuss any one in detail. | 06 |
(b) Discus in detail about Sorensen’s pH scale. | 05 | |
(c) Write a shortnote on “Buffer Equation” | 05 | |
Q.6 | (a) What is White — Vincent method of making isotonic solution? Discuss with suitable example. | 06 |
(b) Discuss in detail about Aerosols. | 05 | |
(c) Give a note on spreading coefficient | 05 | |
Q.7 | (a) Classify the crystals. Discuss about crystal habit. | 06 |
(b) Explain in detail freundlich adsorption isotherm. | 05 | |
(c) Discuss in brief about buffer capacity. | 05 |
Date: 16-11-2019
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Total Marks: 80
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