Download GTU B.Pharma 2019 Winter 4th Sem BP403TP Physical Pharmaceutics Ii Question Paper

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GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 4 EXAMINATION - WINTER -2019
Subject Code: BP403TP Date: 18-12-2019
Subject Name: Physical Pharmaceutics 1T
Time: 02:30 PM TO 05:30 PM Total Marks: 80

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Instructions:

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define Viscosity & explain its application. Discuss Ostwald’s Viscometer 06

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(b) Write a short note on optical properties of colloids. 05
(c) Define : 1) lyophilic colloids, 05
ii) micelles,
iii) Brownian movement,
iv) Faraday-Tyndall effect

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v) Nernst potential

Q.2 (a) Define : i) Kinematic viscosity 06
ii) Thixotropy
iii) Plug flow Rheology
iv) Yield value

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(b) Classify cup and bob viscometer and give examples for each type with principle 05 involved
(c) Draw Rheogram for Newtonian and non-newtonian flow 05

Q.3 (a) Define suspension. Explain sedimentation volume and degree of flocculation 06
(b) Write a note on factor affecting stability of suspension 05
(c) Write a note on suspending-agent. 05

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Q.4 (a) Give a brief account on-theories of emusification. 06
(b) Differentiate between lyophillic and Iyophobic colloids. 05
(c) Write a note on physical stability of emulsion. 05

Q.5 (a) Derive equation of rate of reaction and half life for first order kinetics 06
(b) Discuss different methods to determine order of a reaction. 05

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(c) Write a short note on second order reaction. 05

Q.6 (a) Enlist the methods for particle size determination. Explain conductivity method. 06
(b) Discuss the derived properties of powder. 05
(c) Discuss factors affecting powder flow. 05

Q.7 (a) Write note on Acid-base Enzyme Catalysis. 06

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(b) Ennumarate Physical and chemical factors influencing the chemical degradation 05 of pharmaceutical product and explain any one.
(c) Expalin method for stabilization of medicinal agents from photolytic degradation 05

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