Seat No.:
Subject code: BP505TT
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER-V- EXAMINATION — WINTER 2019
Subject Name: Pharmaceutical Biotechnology
Date: 26/11/2019
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Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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Q.1
- Give application of biotechnology in pharmaceutical sciences. 06
- Enumerate methods of immobilization and explain entrapment in brief. 05
- What are the components of biosensors? 05
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Q.2
- Describe general consideration of enzyme production with flow chart. 06
- Write commercial uses of following industrial enzymes: Amylase, Lipase, Catalase, Protease and Pectinase 05
- Give ideal properties of plasma substitutes. Give the difference between Plasma and Serum 05
Q.3
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- Explain basic steps of recombinant DNA technology with flow diagram. 06
- What are official blood products and explain anticoagulants. 05
- What is PCR? Write its application. 05
Q.4
- Explain Immunoglobulin and write its function. 06
- Describe salient features of MHC. 05
- Differentiate B cell and T cell in immune system. 05
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Q.5
- Enumerate types of hypersensitivity reaction and explain anaphylactive hypersensitivity. 06
- Differentiate Active immunity and Passive immunity 05
- Write application of hybridoma technology. 05
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Q.6
- Describe types of biotransformation reactions. 06
- Differentiate Eukaryotes and Prokaryotes 05
- Explain role of mutation in biotechnology 05
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Q.7
- Give ideal requirement of fermenter and sketch the general diagram of it. 06
- Enumerate the methods of sterilization and explain moist heat sterilization. 05
- Flow diagram of penicillin production by fermentation 05
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