Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 6th Sem 2260003 Pharmaceutical Analysis Iv Previous Question Paper
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 6 EXAMINATION ? WINTER -2019
Subject Code: 2260003 Date: 30-11-2019
Subject Name: Pharmaceutical Analysis IV
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
(a) Define: retention time, retention volume, HETP, copyright, trademark, 06
validation
(b) Explain various modes of HPLC along with stationary phases.
05
(c)
Write a brief note on supercritical fluid chromatography.
05
Q.2
(a) Write a detailed note on HPTLC.
06
(b) List various method validation parameters and explain any three validation 05
parameters.
(c)
List ideal requirements of sample injector. Explain rotary valve injector in 05
HPLC.
Q.3
(a) Explain various characteristics of mobile phase to be kept in mind while 06
selection of solvents in HPLC.
(b) Explain in detail UV- Visible detector in HPLC.
05
(c)
Write a detailed note on columns used in GC.
05
Q.4
(a) Explain electron capture detector and flame ionization detector.
06
(b) Write a brief note on Raman spectrophotometry.
05
(c)
Explain isotope dilution analysis.
05
Q.5
(a) Explain the principle and application of nephelometry and turbidimetry.
06
(b) Describe theory and applications of Radioimmunoassay.
05
(c)
Write a detailed note on stationary phases used in GC.
05
Q. 6
(a) Differentiate the following :
06
1. HPTLC and TLC
2. HPLC and GC
(b) Explain Bragg's law and application of X-ray diffraction.
05
(c)
Explain in detail hyphenation technique, LC-MS.
05
Q.7
(a) Explain the principle and instrumentation of X- ray diffraction spectroscopy.
06
(b) Write a detailed note on GLP.
05
(c)
Explain briefly ISO 9000 standards.
05
***********
This post was last modified on 04 March 2021