Download GTU B.Pharma 2019 Winter 7th Sem 2270002 Pharmaceutical Technology I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 7th Sem 2270002 Pharmaceutical Technology I Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm - SEMESTER? 7th ? EXAMINATION ? WINTER -2019
Subject Code: 2270002
Date:18/11/2019
Subject Name: Pharmaceutical Technology - I
Time: 10:30AM TO 01:30PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write in details about containers used for aerosols. How will you evaluate
06
pharmaceutical aerosols?

(b) Enlist the quality control tests for injectables. Explain rabbit test and LAL test.
05

(c) Define: Pharmaceutical Aerosols. Give a brief account of propellant and its
05
selection.



Q.2 (a) What are the sources of contamination & methods of prevention in sterile
06
dosage formulations?

(b) Draw well labeled diagram for aerosols packs. Explain different parts of valve
05
assembly.

(c) Explain the mechanism of drug penetration through skin. Discuss factors
05
affecting drug absorption through skin from semisolid dosage forms.



Q.3 (a) Write a brief note on formulation of ophthalmic dosage form. Discuss ocular
06
inserts for ophthalmic use.

(b) Write a short note on 1. Prefilled syringes 2. TPN
05

(c) Classify different types of glass as per USP. Describe Water attack test for
05
glass.



Q.4 (a) Enumerate ideal characteristics of suppository bases. Describe methods of
06
manufacturing suppositories in detail.

(b) Write brief note on: 1. Baby care products 2. Hygienic preparations
05

(c) Write a detailed note on storage and purity of W.F.I.
05



Q.5 (a) Comment: Sedimentation rate of flocculated suspensions is faster than
06
deflocculated suspensions. Differentiate flocculated and deflocculated
suspension.

(b) Write brief notes on 1. Tincture 2. Extracts 3. Infusion
05

(c) What are various instabilities of emulsions? Discuss them with their causes and
05
precautions to avoid them



Q. 6 (a) Write brief notes on: 1. SOPs 2. Recovery and reprocessing 3. Personnel
06

(b) Write detailed note on formulation, preparation and evaluation of :
05
1. Sunscreen 2. Nail polish

(c) What are different types of validation? Write short note on validation of
05
granulation stage in tablet manufacturing.



Q.7 (a) Write brief note on formulation, preparation & evaluation of shampoo and
06
conditioners.

(b) Define Validation. Write a note on validation of steam sterilization.
05

(c) Write a note on semi solid bases. Enumerate their selection & ideal requirement 05
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