Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 7th Sem 2270003 Pharm. Chemistry Ix (Med. Chem. Iii) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Ph. - SEMESTER? VII -EXAMINATION ? WINTER -2019
Subject Code: 2270003
Date: 20/11/2019
Subject Name: Pharm. Chemistry-IX (Med. Chem.-III)
Time: 10:30AM TO 01:30PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Write short notes on computer aided drug design.
06
(b) What is Hansch analysis ? Discuss.
05
(c) Discuss Free Wilson mathematical model of QSAR.
05
Q.2 (a) Write detail note on alkylating anticancer agents.
06
(b) What are antiviral and anti HIV agents.
05
(c) What are anthelmintics ? Give synthesis of Albendazole.
05
Q.3 (a) What do you mean by chemotherapeutic agents ? Give SAR of Cephalosporins. 06
(b) Write IUPAC name and synthesis of the following drugs :
05
(i)
Trimethoprim (ii) Sulphacetamide
(c) What are Fluoroquinolones ? Give their SAR.
05
Q.4 (a) What is QSAR ? Discuss electronic parameters in it.
06
(b) Write short notes on combinatorial chemistry.
05
(c) Give synthesis of the following drugs :
05
(i)
Fluorouracil (ii) Tamoxifen
Q.5 (a) What are Aminoglycosides ? Discuss their SAR with examples.
06
(b) Write short note on -lactam antibiotics.
05
(c) Write SAR of Tetracyclines.
05
Q. 6 (a) Write short notes on drugs used for Mycobacterium infection.
06
(b) Classify antifungal agents with examples, How they act.
05
(c) Write IUPAC name and synthesis of the following drugs :
05
(i)
Ketoconazole (ii) Pyrizinzmide
Q.7 (a) What is malaria ? How it spreads? Classify antimalarial drugs with examples.
06
(b) Give synthetic routes of the following drugs :
05
(i)
Primaquine (ii) Metronidazole
(c) Write short notes on Antiamoebic agents.
05
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This post was last modified on 04 March 2021