Download GTU B.Pharma 2019 Winter 7th Sem 2270004 Pharmacology And Pharmacotherapeutics Iii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 7th Sem 2270004 Pharmacology And Pharmacotherapeutics Iii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 7 EXAMINATION ? WINTER -2019
Subject Code: 2270004 Date: 22-11-2019
Subject Name: Pharmacology and Pharmacotherapeutics ? III
Time: 10:30AM TO 01:30PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1
(a) Write the mechanism of action and side effects of :
06
I.Indinavir II. Rifampin III. Amphotericin- B

(b) Explain various mechanisms of drug resistance with suitable examples.
05

(c) Discuss pathogenesis and treatment of Urinary Tract infections.
05



Q.2
(a) Explain various forms of influenza virus infections. Write etiopathogenesis of
06
SARS and its treatment.

(b) Discuss adverse effects of Chloramphenicol and Tetracycline.
05

(c) Write a note on Tamoxifen
05



Q.3
(a) Describe the pharmacology of drugs for the treatment of luminal amoebiasis.
06

(b) Discuss advantages and use of semisynthetic penicillins.
05

(c) Discuss pathophysiology, symptoms, diagnosis and treatment of Syphilis and
05
Gonorrhoea.



Q.4
(a) Describe the spectrum of activity, adverse effects and therapeutic uses of
06
Fluoroquinolones.

(b) Justify the following:
05
I. Sulphonamide potency is decreased in case of co-administration with Local
anesthetics
II. Amoxicillin is preferred to ampicillin
III.Pateints on procarbazine should avoid wine and cheese in their diet.
IV.Allopurinol is used to decrease excessive uric acid formation during cancer
theraphy.
V.Penicillin is a drug of choice for syphilis treatment

(c) Compare and contrast Penicillins and cephalosporins
05



Q.5
(a) Classify aminoglycosides. Describe their spectrum, adverse effects and
06
indications of 'Streptomycin'.

(b) Explain the Role of Vinca alkaloids and taxanes in cancer.
05

(c) Write a note on Azole antifungal agents
05



Q. 6 (a) Classify cephalosporins. Describe the antibacterial spectrum, therapeutic uses
06
and adverse effects of third generation cephalosporin's

(b) write a note on Treatment of multibacillary leprosy
05

(c) write a note on Beta lactamase inhibitors
05



Q.7
(a) Enumerate macrolides. Discuss the actions, uses & side effects of
06
Erythromycin

(b) Write the Mode of action and therapeutic uses of :
05
d ? pencillamine Oseltamivir Cefaclor Imipinem Aztreonam

(c) Explain signs ,symptoms, diagnosis and treatment of tuberculosis.
05
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