Download GTU B.Pharma 2019 Winter 8th Sem 2280003 Pharmaceutical Chemistry X (Medicinal Chemistry Iii) Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 8th Sem 2280003 Pharmaceutical Chemistry X (Medicinal Chemistry Iii) Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 8 EXAMINATION ? WINTER -2019
Subject Code: 2280003 Date: 19-11-2019
Subject Name: Pharmaceutical Chemistry ? X (Medicinal Chemistry - III)
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a)
Classify Antidiabetics. Give synthesis of Glimipiride
06

(b)
Give SAR of Dihydropyridines
05

(c)
Give synthesis of Metoprolol and Amlodipine
05



Q.2 (a)
Classify antiarrhyyhmic agents. Give synthesis of Lignocaine
06

(b)
Discuss SAR of ACE inhibitors.
05

(c)
Give account of coagulants and anticoagulants. Give synthesis of warfarin
05



Q.3 (a)
Discuss recent developments in antihyperlipidemic agents
06

(b)
Give SAR of HMG Co-A reductase inhibitors. Give synthesis of Clofibrate
05

(c)
What is Obesity? Write a note on antiobesity drugs
05



Q.4 (a)
Write a note on antianginal agents
06

(b)
Discuss in brief thrombolytic agents.
05

(c)
What are plasma expanders? Provide their chemistry
05



Q.5 (a)
Discuss adrenocorticoides.
06

(b)
Explain nomenclature and stereochemistry of steroids
05

(c)
Write a note on cardiac glycosides.
05



Q. 6 (a)
Write a brief note on sex hormones
06

(b) What are antithyroid agents ? Classify with examples.
05

(c)
Give details on antiplatelet agents
05



Q.7
(a) What are diuretics? Give details of 5-Sulfamoyl benzoic acid derivatives
06

(b)
Give synthesis of Acetazolamide and Ethacrinic acid
05

(c)
What are immunomodulators? Discuss about each in detail
05
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