Download GTU B.Pharma 2019 Winter 2nd Sem 2220001 Physical Pharmacy Question Paper

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Seat No.:

Subject Code: 2220001

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Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER- 2 EXAMINATION - WINTER -2019

Subject Name: Physical Pharmacy

Time: 10:30 AM TO 01:30 PM

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Instructions:

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1

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1. Classify organic molecular complexes. Describe nature of reactions of it with suitable examples. (06)
2. Enlist methods to study protein binding. Explain any one method in detail. (05)
3. Write a short note on applications of complexes in dosage form. (05)

Q.2

1. Discuss the influence of solvents and surfactants on solubility. (06)

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2. Define partition coefficient. Discuss its importance in pharmaceutical systems. (05)
3. Write a short note on solubility of gases in liquids. (05)

Q.3

1. Discuss the binding forces present between molecules. (06)
2. What is phase rule? Explain phase diagram of water. (05)

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3. Write a short note on liquid crystals. (05)

Q.4

1. What is HLB? Describe any one method to determine it. (06)
2. Define following:
   I) Porosity II) Kinematic Viscosity III) Surface Tension
   

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   IV) Condensed System V) Supersaturation (05)
3. Write a short note on applications of colloids in pharmacy. (05)

Q.5

1. Discuss the factors influencing physical stability of suspensions. (06)
2. Explain in detail about-causes for the instability of emulsions. (05)

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3. Explain the working principle of Coulter Counter with the help of a neat diagram. (05)

Q.6

1. Describe various way of quantifying the flow of powder. (06)
2. Discuss methods for determination of particle size diameter. (05)
3. Explain Air permeability method with a neat diagram. (05)

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Q.7

1. Explain in detail about plastic and pseudoplastic flow with suitable examples. (06)
2. Describe working principle of Ostwald viscometer with labeled diagram. (05)
3. Discuss factors influencing viscosity. (05)

Total Marks: 80

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Date: 21-12-2019