Download GTU B.Pharma 2019 Summer 2nd Sem BP202TP Pharmaceutical Organic Chemistry I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 2nd Sem BP202TP Pharmaceutical Organic Chemistry I Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 2 EXAMINATION ? SUMMER -2019
Subject Code: BP202TP Date: 29-05-2019
Subject Name: Pharmaceutical Organic Chemistry I
Time: 10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Give IUPAC name of followings:
06

(b) Write all possible isomers of C4H8 and name them by IUPAC system.
05

(c) Define and classify organic compound. Explain SP3 hybridization of alkane.
05



Q.2 (a) Give the structure and uses of the following
06
(1) Chlorobutanol (2) Methyl salicylate (3) Hexamine
(4) Vanillin (5) Paraldehyde (6) Ethylenediamine

(b) Describe effect of substituent on basicity of aliphatic amine. Why 2? amine is
05
more basic than 1? and 3? amine in aqueous media?

(c) Give three methods for synthesis of alkenes.
05



Q.3 (a) Explain reaction mechanism of cannizzaro reaction and perkin condensation.
06

(b) Explain acidity of carboxylic acid in brief. What is the impact on acidity of
05
benzoic acid if it was substituted with ?OH or ?CH3?

(c) Mention method of preparation for carboxylic acid. Give any two qualitative
05
tests for identification of carboxylic acid.



Q.4 (a) Write Aldol condensation &Cross aldol condensation with reaction mechanism. 06

(b) Explain method for synthesis of alkyl halides.
05

(c) Describe the factors affecting the E1 and E2 reaction.
05



Q.5 (a) Give general mechanism for nucleophilic addition of carbonyl compounds.
06
Mention any three nucleophilic addition reactions of aldehyde or ketone.

(b) Explain ozonolysis of alkene in detail.
05

(c) Describe stability of conjugated dienes.
05



Q. 6 (a) Differentiate Markownikoff's addition and Anti-markownikoff's addition to
06
alkene.

(b) Explain Saytzeff rule with examples.
05

(c) What is pyrolysis? Give general reaction of pyrolysis for alkane.
05



Q.7 (a) How will you distinguish 1?, 2? and 3? alcohol? Explain Grignard reaction for
06
synthesis of alcohols.

(b) Write note on Diel-Alder reaction.
05

(c) Write short notes on SN1 reaction in detail.
05
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