Download GTU B.Pharma 2019 Summer 3rd Sem 230001 Physical Pharmaceutics Ii Question Paper

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Seat No.:

Subject Code: 230001

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Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER- 3 EXAMINATION - SUMMER -2019

Subject Name: Physical Pharmaceutics - 11

Time: 02:30 PM TO 05:30 PM

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Instructions:

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

1. (a) Explain effect of dielectric constant on rate constant. (06)

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2. (b) Write short note on: Beckmann's freezing point apparatus. (05)
3. (c) What are colligative properties? Describe boiling point elevation. (05)
4. (a) Discuss Arrhenius theory of electrolytic dissociation. (06)
5. (b) Discuss ideal and real solutions with suitable examples. (05)
6. (c) Explain: Molarity, Molality, Normality, Formality, Gram per liter. (05)

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7. (a) Define first order reaction. Derive equations for first order reaction and its half-life and shelf-life. (06)
8. (b) Enumerate factors affecting the rate of reaction. Explain effect of temperature on it. (05)
9. (c) Define order of reaction. Describe methods used to determine the same. (05)
10. (a) What is accelerated stability analysis? Describe ICH guidelines for stability study. (05)
11. (b) Describe the various drug decomposition pathways with remedial measures. (05)

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12. (c) Define Hydrogels. Classify and explain its role in drug delivery system. (06)
13. (a) Write detail about the applications of complexes in pharmacy. (05)
14. (b) Explain the kinetics of protein binding. (05)
15. (c) Classify the complexes and explain importance of chelates in metal ion complexes. (06)
16. (a) Describe the pharmaceutical applications of polymers. (05)

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17. (b) Define polymers. Give detailed classification of polymers. (05)
18. (c) Enlist synthetic polymers. Discuss any two general properties of polymer solutions. (06)
19. (a) Describe the method for studying in vitro drug diffusion. (05)
20. (b) What is dissolution? Discuss its significance in drug therapy. (05)
21. (c) Describe in vitro dissolution test apparatus as per Indian Pharmacopoeia. (05)

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Date: 30-05-2019

Total Marks: 80