Download GTU B.Pharma 2019 Summer 3rd Sem BP302TP Physical Pharmaceutics I Question Paper

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Seat No.:

Subject Code: BP302TP

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Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER- 3 EXAMINATION - SUMMER -2019

Subject Name: Physical Pharmaceutics I

Time: 02:30 PM TO 05:30 PM

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Instructions:

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

1. (a) Describe Raoult’s law with its application. 06

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2. (b) Define following terms 05
   1. Solution
   2. Solute
   3. Solvent
   4. Saturated solution
   5. Supersaturated solution.

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3. (c) Enumerate factors affecting solubility and discuss common ion effect in detail. 05

1. (a) Discuss the factors affecting solubility of gas in liquids. 06
2. (b) What is polymorphism? Discuss it with suitable examples. 05
3. (c) Briefly explain (i) Glassy state and (ii) Liquid crystals. 05

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1. (a) Explain sublimation with suitable diagram. 06
2. (b) What is the significance of specific rotation in pharmacy? 05
3. (c) Write a note on Du Nouy Tensiometer. 05

1. (a) Explain spreading coefficient. 06
2. (b) Give the range of HLB value of’ (1) Detergents (ii) wetting agents (iii) o/w emulsifying agents (iv) Antifoaming agents (v) Solubilizing agents 05

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3. (c) What is physisorption? Differentiate physisorption and chemisorptions. 05

1. (a) Explain the significance of protein binding. 06
2. (b) Write a short note on Clathrates. 05
3. (c) Write a short note on ligands. 05

1. (a) Classify the complexes and explain chelates in detail. 06

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2. (b) Explain Sorensen’s pH scale. 05
3. (c) Write a note on pH determination. 05

1. (a) Explain Henderson-Hasselbalch equation. 06
2. (b) What are the methods of adjusting tonicity? Discuss freezing point method in detail. 05
3. (c) Explain the limitation of distribution law. 05

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Date: 30-05-2019

Total Marks: 80

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