Download GTU B.Pharma 2019 Summer 5th Sem 2250005 Pharmacology And Pharmacotherapeutics I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 5th Sem 2250005 Pharmacology And Pharmacotherapeutics I Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 5 EXAMINATION ? SUMMER -2019
Subject Code: 2250005 Date: 06-06-2019
Subject Name: Pharmacology and Pharmacotherapeutics?I
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Give comment on following:
06
(i) -blockers may cause cold extremeties.
(ii) Clonidine is anti-hypertensive agent.
(iii) Edrophonium is used in diagnosis of myasthenia gravis.

(b) Write name of receptor involved and physiological response(s) produced by 05
parasympathetic nerve activation in following organ:
(i) Iris (ii) Small intestine (iii) Urinary bladder (iv) Heart (v) Salivary gland

(c) Outline biosynthesis of prostaglandins. Discuss their physiological role.
05



Q.2 (a) Explain following: (i) Dale's vasomotor reversal (ii) Co-transmission
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(iii) Synaptic fatigue

(b) Classify drugs used in migraine. Discuss role of 5-HT in pathogenesis of
05
migraine.

(c) Write pharmacology of angiotensin.
05



Q.3 (a) Classify skeletal muscle relaxants. Write pharmacology of d-tubocurarine.
06

(b) Write pathogenesis of peptic ulcer. Classify drugs used in treatment of peptic
05
ulcer.

(c) Discuss management of asthma.
05



Q.4 (a) Give comment on following:
06
(i) Atropine is used as pre-anaesthetic medication.
(ii) -blockers may produce postural hypotension.
(iii) Montelukast is used in treatment of asthma.

(b) Describe management of diarrhoea with special emphasis on oral rehydration
05
therapy.

(c) Classify anti-histaminic agents. Add a note on non-sedative anti-histaminic
05
agents.



Q.5 (a) Draw diagrammatic representation of adrenergic transmission. Describe how
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action of nor-adrenaline is terminated at synapse?

(b) Write symptoms of organophosphorus poisoning. Describe role of pralidoxime
05
in management of organophosphorus poisoning.

(c) Classify anti-emetics. Add a note on ondansetron.
05



Q. 6 (a) Classify local anaesthetic agents. Discuss various techniques of local
06
anaesthesia in brief.

(b) Write etiology, symptoms and treatment for inflammatory bowel syndrome.
05

(c) Classify laxatives. Add a note on irritant laxatives.
05



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Q.7 (a) Describe type, pathogenesis and treatment for glaucoma.
06

(b) Discuss diagnosis and management of hepatitis A.
05

(c) Draw structure of nicotinic receptor. Write location and physiological role of
05
nicotinic receptors in brief.
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