Seat No.:
Subject Code: 2260003
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 6 EXAMINATION - SUMMER -2019
Subject Name: Pharmaceutical Analysis IV
Time: 02:30 PM TO 05:30 PM
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Date: 08-05-2019
Total Marks: 80
Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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- (a) Explain Bragg’s law and write a note on different method for x-ray diffraction study. (06)
- (b) Write a note on GLP. (05)
- (c) Explain the Principle of Ion exchange and Super critical Fluid chromatography. (05)
- (a) Explain the Principle of Gas Chromatography. Enlist the detectors used in GC and explain any one. (05)
- (b) Explain the Various steps involved in Patent filling. (05)
- (c) Give the application of X-ray diffraction study. (06)
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- (a) Discuss the Principle and application of HPLC. (05)
- (b) Write a note on Raman spectroscopy. (05)
- (c) Give an overview of LC-MS/MS. (06)
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- (a) Write a short note on Affinity chromatography. (05)
- (b) Give a brief note on GC-MS. (05)
- (c) Write a note on ISO 9001:2000. (06)
- (a) Write a note on RIA. (05)
- (b) Give brief idea about HETP, Peak asymmetry factor, Resolution. (05)
- (c) Write a note on GATT and TRIPS. (06)
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- (a) Discuss in detail on HPLC instrumentation. (05)
- (b) Explain principle, methodology and application of ELISA. (05)
- (c) Write a note on Isotope dilution analysis. (06)
- (a) Discuss the Principle and Instrumentation of HPTLC. (05)
- (b) Write a note on Neutron Activation Analysis. (05)
- (c) Enlist the parameters for Analytical Method Validation as per ICH guidelines and discuss on Accuracy and Precision. (06)
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