Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 7th Sem 270003 Pharmaceutical Chemistry Ix (Medicinal Chemistry) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 7 EXAMINATION ? SUMMER -2019
Subject Code: 270003 Date: 13-05-2019
Subject Name: Pharmaceutical Chemistry-IX (Medicinal Chemistry)
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) What are sulfonamides? Write Mechanism of action and SAR of Sulfonamides.
06
(b) Briefly explain SAR of Fluoroquinolones.
05
(c) Write synthesis of Thiotepa and Chloramphenicol
05
Q.2 (a) Write Mechanism of action, uses, side effects and degradation of Penicllins.
06
(b) Write detail SAR of Cephalosporins.
05
(c) Write short notes on Aminoglycosides antibiotics.
05
Q.3 (a) Briefly explain SAR of Tetracyclines.
06
(b) Write mechanism of action, chemistry and uses of Macrolide antibiotics.
05
(c) Write synthesis of Isoniazid and Chloroquine.
05
Q.4 (a) What are antitubercular agents ? Briefly explain first line antitubercular agents.
06
(b) Write short notes on Antifungal agents.
05
(c) Write synthesis of Albendazole and Metronidazole
05
Q.5 (a) Briefly explain Antiviral agents.
06
(b) What are immunomodulators? Write detail notes on Immunosuppressive
05
agents.
(c) Write synthesis of Amantadine and Tamoxifen
05
Q. 6 (a) What are antineoplastic agents? Write detail notes on Alkylating anticancer
06
agents.
(b) Write short notes on antimetabolite anticancer agents.
05
(c) Explain antithyroid drugs. Write synthesis of Methimazole.
05
Q.7 (a) What is diabetes? Write detail notes on oral hypoglycemic agents.
06
(b) Briefly explain nomenclature and stereochemistry of steroids.
05
(c) Write detail SAR on Adrenocorticoids.
05
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This post was last modified on 04 March 2021