Download GTU B.Pharma 2019 Summer 8th Sem 2280002 Pharmaceutical Technology Ii Question Paper

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GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER- 8 EXAMINATION - SUMMER -2019

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Subject Code: 2280002 Date: 08-05-2019

Subject Name: Pharmaceutical Technology II

Time: 10:30 AM TO 01:30 PM Total Marks: 80

Instructions:

1. Attempt any five questions.

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2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1

1. (a) Describe film coating defects in tablets with remedies. [06]
2. (b) Explain in brief compression and compaction of tablets. [05]

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3. (c) Write a note on Tablet compression Tooling. [05]

Q.2

1. (a) Discuss in-process quality control tests of tablets. [06]
2. (b) Explain in brief capping and lamination defects of tablets. [05]
3. (c) Write objectives of coating. Discuss various film forming materials. [05]

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Q.3

1. (a) Write specific evaluation tests of mouth dissolving tablets & floating tablets. [06]
2. (b) Write applications of biodegradable and non biodegradable polymers used in Microcapsules/Microspheres. [05]
3. (c) Enumerate the techniques of microencapsulation. Describe working of “Wurster Air Suspension Apparatus”. [05]

Q.4

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1. (a) Explain the defects observed in manufacturing of hard gelatin capsules. [06]
2. (b) Write manufacturing process of Hard Gelatin Capsule Shells. [05]
3. (c) Describe rotary die process of manufacturing soft gelatin capsule with schematic diagram. [05]

Q.5

1. (a) Discuss factors affecting pellet properties. Write Melt extrusion method of pellet preparation. [06]

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2. (b) Explain : Tamper-evident packaging, Child resistant containers. [05]
3. (c) Discuss importance of climatic control in capsule department. [05]

Q.6

1. (a) Explain phase diagram with labeled sketch shows supercritical region with examples. [06]
2. (b) Write pharmaceutical applications of supercritical fluid. [05]

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3. (c) Discuss regulatory requirements in packaging. [05]

Q.7

1. (a) Describe the methods for the filling of Hard Gelatin capsules. [06]
2. (b) Write a short note on evaluation tests of pharmaceutical packaging materials. [05]
3. (c) Describe preparation method of powder from liquid by using supercritical fluids. [05]

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