Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.PHARM - SEMESTER- 8 EXAMINATION - SUMMER -2019
Subject Code: 280004 Date: 14-05-2019
Subject Name: Pharmaceutical Analysis-1V
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
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- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Explain Bragg’s law. Explain different method for x-ray diffraction study. 06
(b) Explain application of x-ray diffraction study. 05
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(c) Write a short note on GLP. 05
Q.2 (a) Write a short note on Raman spectroscopy. 06
(b) Differentiate Nephelometer and Turbidometer. Explain Nephelometer. 05
(c) Write a short note on ISO. 05
Q.3 (a) Explain theories of Chromatography. 06
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(b) Explain instrumentation and application of HPLC. 05
(c) Write a note on steps involved in patent filing. 05
Q.4 (a) Explain Affinity Chromatography in detail. 06
(b) Write a note on Size Exclusion Chromatography 05
(c) Explain different types of resins in Ion-Exchange Chromatography. Explain 05 instrumentation and applications ion exchange chromatography.
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Q.5 (a) Explain different types of RIA in-detail. 06
(b) Write short note on HPTLC: 05
(c) Discuss various parameters-of analytical method validation. 05
Q.6 (a) Explain principle and application of Gas chromatography. 06
(b) Explain different detectors used in Gas chromatography. 05
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(c) Differentiate HPLC and GC. 05
Q.7 (a) Write a short note on supercritical fluid chromatography. 06
(b) Give a brief note on GC-MS. 05
(c) Write a short note on ELISA. 05
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