Download GTU B.Pharma 2018 Winter 4th Sem 240005 Pharmacology I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 4th Sem 240005 Pharmacology I Previous Question Paper

Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 4- EXAMINATION ?WINTER - 2018

Subject Code:240005
Date: 10/12/2018
Subject Name: Pharmacology - I
Time:02:30 PM TO 05:30 PM
Total Marks: 80

Instructions:

1. Attempt any five questions.

2. Make Suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

Q.1 (a) Classify parasympathomimetics. Write M/A and therapeutic uses of Ach.
06

(b) Explain pharmacokinetic drug- drug interactions with examples.
05

(c) Write a note on enzyme induction and enzyme inhibition with examples.
05



Q.2 (a) Classify beta blockers. Write a pharmacological action and uses of propranolol.
06

(b) Differentiate competitive and non-competitive antagonism.
05

(c) Explain drug tolerance and dependence.
05



Q.3 (a) Classify serotonin receptors and describe its pharmacological actions.
06

(b) Write merits and demerits of intravenous route.
05

(c) Write different phases of clinical trials.
05



Q.4 (a) Classify alpha-adrenoreceptor antagonist. Describe pharmacology of prazosin.
06

(b) Explain various factors modifying drug action.
05

(c) Describe mode of action and therapeutic uses of local anaesthetics.
05



Q.5 (a) Classify antihistamines and give its pharmacological action and therapeutic
06
uses.

(b) Write a note on apparent volume of distribution.
05

(c) Write a short note on acute and sub acute toxicity study.
05



Q. 6 (a) Classify neuromuscular blockers. Write on M/A and uses of d-tubocurarine.
06

(b) Explain bioavailability and its significance.
05

(c) Write a note on organophosphorous poisoning.
05



Q.7 (a) Write in brief the gating and signal transduction mechanisms of G-protein
06
coupled receptors.

(b) Write a note on prostaglandins.
05

(c) Explain the term of biological half life and give its importance.
05
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