GTU B.Pharm 2018 Winter Question Papers || Gujarat Technological University
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Seat No.:
Subject Code: 2260004
Time: 02:30 PM TO 05:30 PM
Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER - 6- EXAMINATION -WINTER - 2018
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Define sedatives and hypnotics. Classify with examples. Discuss general method of synthesis of barbiturates. 06
(c) What is Alzheimer’s disease? Discuss its cause and treatment. 05
Q.2 (a) What is Phase-II metabolism? How glucoronide conjugation helps to metabolized drug molecules. Explain with examples. 06
(b) Write note on anti-gout drugs. 05
(c) Write synthesis of Lignocaine and discuss its mode of action. 05
(b) Explain Various Forces involved in Drug-Receptor Interaction 05
(c) Write synthesis of 1) Halothane ii ) Chlorpromazine 05
Q.4 (a) Write synthesis of any two: 06
1) Ibuprofen
3) Phenytoin
(b) Classify and Explain Hallucinogens in detail. 05
(c) Write synthesis of 1) L-Dopa ii) Diclofenac 05
Q.5 (a) Describe various forces involved in drug receptor interaction with examples. 06
(c) Write synthesis of drugs 1) xylocaine ii) Thiopental sodium 05
Q.6 (a) Define antipsychotic agents. Write detailed SAR of phenothiazines. 06
(b) Explain different types of epilepsy. Classify epileptic agents with examples. 05
(c) Write note on anti-anxiety agents. 05
(b) What are CNS depressants. Write SAR of butyrophenones. 05
(c) What is Cytochrome P-450? Explain its role and function in Xenobiotic Metabolism 05
Date: 29/11/2018
Total Marks: 80
Seat No.:
Subject Code: 2260004
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Subject Name: Pharmaceutical Chemistry - VIII (Medicinal Chemistry - II)Time: 02:30 PM TO 05:30 PM
Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER - 6- EXAMINATION -WINTER - 2018
--- Content provided by FirstRanker.com ---
Instructions:1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Define sedatives and hypnotics. Classify with examples. Discuss general method of synthesis of barbiturates. 06
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(b) Discuss SAR of local anesthetics having amide linkage in their structures. 05(c) What is Alzheimer’s disease? Discuss its cause and treatment. 05
Q.2 (a) What is Phase-II metabolism? How glucoronide conjugation helps to metabolized drug molecules. Explain with examples. 06
(b) Write note on anti-gout drugs. 05
(c) Write synthesis of Lignocaine and discuss its mode of action. 05
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Q.3 (a) Enlist and explain factors affecting drug-receptor interaction. 06(b) Explain Various Forces involved in Drug-Receptor Interaction 05
(c) Write synthesis of 1) Halothane ii ) Chlorpromazine 05
Q.4 (a) Write synthesis of any two: 06
1) Ibuprofen
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2) Nimesulide3) Phenytoin
(b) Classify and Explain Hallucinogens in detail. 05
(c) Write synthesis of 1) L-Dopa ii) Diclofenac 05
Q.5 (a) Describe various forces involved in drug receptor interaction with examples. 06
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(b) Discuss SAR of Tricyclic Antidepressant drugs with suitable example. 05(c) Write synthesis of drugs 1) xylocaine ii) Thiopental sodium 05
Q.6 (a) Define antipsychotic agents. Write detailed SAR of phenothiazines. 06
(b) Explain different types of epilepsy. Classify epileptic agents with examples. 05
(c) Write note on anti-anxiety agents. 05
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Q.7 (a) Write short notes on analeptic agents. 06(b) What are CNS depressants. Write SAR of butyrophenones. 05
(c) What is Cytochrome P-450? Explain its role and function in Xenobiotic Metabolism 05
Date: 29/11/2018
Total Marks: 80
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