Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 8th Sem 2280003 Pharmaceutical Chemistry X (Medicinal Chemistry Iii) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 8- EXAMINATION ?WINTER - 2018
Subject Code: 2280003
Date: 19/11/2018
Subject Name: Pharmaceutical Chemistry ? X (Medicinal Chemistry - III)
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Give the method of synthesis of
06
(i) Warfarin (ii) Metformin (iii) Carbimazole
(b) Write informative note on Anti platelet Agents
05
(c) What is obesity? Write a note on antiobesity drugs.
05
Q.2 (a) Discuss the SAR among Cardiac glycosides.
06
(b) Write short note on immunomodulators.
05
(c) Give the method of synthesis of (i) Lignocaine (ii) Atenolol
05
Q.3 (a) Give the method of synthesis of
06
(i) Clofibrate (ii) Ethacrinic acid (iii) Glimipride
(b) Discuss the SAR among
05
(i) Estrogens (ii) Dihydropyridnes
(c) Write short notes on Thrombolytic agents.
05
Q.4 (a) Define and classify Diuretic Agents. Discuss the SAR among Progestins and
06
Androgens.
(b) Write detail note on Cardio tonic Agents.
05
(c) Write down notes on Coagulants and Anticoagulants.
05
Q.5 (a) What are the causes of hypertension ? Write a note on -blockers.
06
(b) Define and classify Hypoglycemic Agents.
05
(c) Give SAR of ACE inhibitors.
05
Q. 6 (a) What is Diabetes ? Classify antidiabetics with examples and give their
06
mechanism of action.
(b) Discuss the SAR among
05
(i) Thiazide Diuretics (ii) 5- Sulfamoyl Benzoic acid derivatives.
(c) Discuss detail about Plasma expanders
05
Q.7 (a) Explain in detail the nomenclature and stereochemistry of Steroidal
06
Compounds.
(b) Discuss the SAR among HMG CoA Reductase inhibitors.
05
(c) Give the method of synthesis of (i) Acetazolamide (ii) Captopril
05
***************
This post was last modified on 04 March 2021