Download OU B.Pharma 2-1 Year 2010 4407 Pharmaceutical Organic Chemistry I Question Paper

Download OU (Osmania University) B.Pharma 2-1 (2nd Year 1st Sem) (Bachelor of Pharmacy) 2010 4407 Pharmaceutical Organic Chemistry I Previous Question Paper

11101111111 Code No. : 4407
FACULTY OF PHARMACY
B. Pharm. II Year I Semester Main Examination, November/December 2010
PHARMACEUTICAL ORGANIC CHEMISTRY ? I
Time : 3 Hours] [Max. Marks : 70
Note : Answer all questions. All questions carry equal marks.
1. a) What are the different type of bonds you have studied ? Describe in detail
about covalent bond and polarity of covalent bond. 10
131 Write a note on solubility. 4
OR
c) Write in detail about acidity and basicity of organic molecules. 8
d) What is isomerism ? Explain with suitable example. 6
2. a) Define Electrophilic addition reaction of alkenes and explain with suitable
examples. 14
OR
b) What are cycloalkanes ? Write any 3 methods of preparation and stability of
cycloalkanes with reference to Bayer's strain theory. 14
3. a) What is the type of chemical reaction takes place when alcoholic potassium
hydroxide and aqueous potassium hydroxide are reacted with alkyl halide ? 4
b) Explain the mechanism of
i) SN
I
and SN
2
reaction
ii) E
t
and E
2
reaction.
OR
(This paper contains 2 pages)
5+5=10
1 P.T.O.
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11101111111 Code No. : 4407
FACULTY OF PHARMACY
B. Pharm. II Year I Semester Main Examination, November/December 2010
PHARMACEUTICAL ORGANIC CHEMISTRY ? I
Time : 3 Hours] [Max. Marks : 70
Note : Answer all questions. All questions carry equal marks.
1. a) What are the different type of bonds you have studied ? Describe in detail
about covalent bond and polarity of covalent bond. 10
131 Write a note on solubility. 4
OR
c) Write in detail about acidity and basicity of organic molecules. 8
d) What is isomerism ? Explain with suitable example. 6
2. a) Define Electrophilic addition reaction of alkenes and explain with suitable
examples. 14
OR
b) What are cycloalkanes ? Write any 3 methods of preparation and stability of
cycloalkanes with reference to Bayer's strain theory. 14
3. a) What is the type of chemical reaction takes place when alcoholic potassium
hydroxide and aqueous potassium hydroxide are reacted with alkyl halide ? 4
b) Explain the mechanism of
i) SN
I
and SN
2
reaction
ii) E
t
and E
2
reaction.
OR
(This paper contains 2 pages)
5+5=10
1 P.T.O.
MENU Code No. : 407
c) Write in brief about the preparations and reactions of Ethers.
10
d) Write a note on oxidation of alcohols.
4
4. a) Write the various Nucleophilic addition reactions of carbonyl compounds
with mechanism. 8
b) Write any two methods of preparation of carbonyl compounds. 6
OR
c) Write the synthetic applications of Acetoacetic ester and malonic ester. 8
d) Write any two methods of preparation of acid derivatives. 6
5. a) Write the Nomenclature and acidity of Nitro alkanes. 7
b) Write the methods of preparation of Nitro alkanes. 7
OR
c) Write the synthetic applications of Diazonium salts. 7
d) Write in brief about the reactions of amines. 7
2 1,900
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