Download OU (Osmania University) B.Pharma 2-1 (2nd Year 1st Sem) (Bachelor of Pharmacy) 2010 4409 Pharmaceutical Analysis I (Chemical Analysis) Previous Question Paper
FACULTY OF PHARMACY
B. Pharmacy II Year I Sem. (Main) Examination, November/December 2010
PHARMACEUTICAL ANALYSIS ? I (Chemical Analysis)
Time : 3 Hours] [Max. Marks: 70
Note : Answer all questions. All questions carry equal marks.
1. a) i) Define and explain. 6
A) Relative Error B) Indeterminate Error C) Gross Error
ii) Describe the methods of expressing concentration. 4
iii)Calculate the equivalent weight of the following : 4
A) K
2
Cr
2
O
7
B) NaOH C) H
2
SO
4
D) KMNO
4
OR
b) i) What are Primary standard and Secondary standard substances ?
Mention few examples of each. 7
ii) The following results were obtained in the replicate analysis of a blood
sample for its lead content 0.754, 0.756, 0.752, 0.751 and 0.760 PPM pb.
Calculate the Mean, Standard deviation, Range and Median. 7
2. a) i) What is common Ion Effect ? Discuss its applications in pharmaceutical
analysis. 8
ii) Discuss the modern concepts of acidity and basicity. Give some examples. 6
OR
b) i) How much water is to be added to a 150 ml of solution of 0.25N HC1
to make it 0.1 N solution ? 4
ii) Write a note on neutralization indicator. 4
iii)Derive an equation to calculate the pH value of an aqueous solution
of a salt of weak acid and strong base. 6
3. a) i) Write a note on 4
A) Coagulation B) Digestion
ii) Explain the theories involved for determination of chloride in 10
A) Mohr's method B) Volhard's method C) Fajan's method
OR
(This paper contains 2 pages) 1 P.T.O.
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Code No. : 4409
FACULTY OF PHARMACY
B. Pharmacy II Year I Sem. (Main) Examination, November/December 2010
PHARMACEUTICAL ANALYSIS ? I (Chemical Analysis)
Time : 3 Hours] [Max. Marks: 70
Note : Answer all questions. All questions carry equal marks.
1. a) i) Define and explain. 6
A) Relative Error B) Indeterminate Error C) Gross Error
ii) Describe the methods of expressing concentration. 4
iii)Calculate the equivalent weight of the following : 4
A) K
2
Cr
2
O
7
B) NaOH C) H
2
SO
4
D) KMNO
4
OR
b) i) What are Primary standard and Secondary standard substances ?
Mention few examples of each. 7
ii) The following results were obtained in the replicate analysis of a blood
sample for its lead content 0.754, 0.756, 0.752, 0.751 and 0.760 PPM pb.
Calculate the Mean, Standard deviation, Range and Median. 7
2. a) i) What is common Ion Effect ? Discuss its applications in pharmaceutical
analysis. 8
ii) Discuss the modern concepts of acidity and basicity. Give some examples. 6
OR
b) i) How much water is to be added to a 150 ml of solution of 0.25N HC1
to make it 0.1 N solution ? 4
ii) Write a note on neutralization indicator. 4
iii)Derive an equation to calculate the pH value of an aqueous solution
of a salt of weak acid and strong base. 6
3. a) i) Write a note on 4
A) Coagulation B) Digestion
ii) Explain the theories involved for determination of chloride in 10
A) Mohr's method B) Volhard's method C) Fajan's method
OR
(This paper contains 2 pages) 1 P.T.O.
1111111111111 1 111111 Code No. : 4409
b) i) What is oxidation-reduction potential and write how it is determined
the redox system ?
ii) What are Redox Indicators ? What is the chemical process causes them
to change color ? 6
iii) Calculate the normality of the following 2M K
2
Cr
2
O
7
.
4. a) i) How do you prepare and standardise the following solutions 8
A) 0.01M EDTA B) 0.1N HC10
4
ii) How do you estimate the hardness of water using complexometry ? 6
OR
b) i) What is the difference between Iodometry and Iodimetry ? Explain with
the help of one suitable examples. Write the principle and procedure of
Iodometric assay of any official compound. 10
ii) Write a note on different solvents used in Non-aqueous titration. 4
5. a) i) How much is mass of NaOH required to convert 7.3 g of HC1 to NaC1 ? 4
ii) Calculate the percentage composition of elements in Na
2
S
2
O
3
(Atomic weight Na, S, 0 are 23, 32, 16 respectively ) 4
iii) Define Stoichiometry, mole and percentage yield. 6
OR
b) i) How will you balance the following equation by applying Ion-electron
method ? 5
KMnO
4
+ FeSO
4
+ H
2
SO
4
->Fe
2
(SO
4
)
3
+ K
2
SO
4
+ MnSO
4
+ H2O
ii) What is Avagadro's number ? Explain how the moles of elements
are measured. 7
iii) Calculate the normality of 10 milli moles of Na
2
S
2
O
3
in 200 ml
of solution. 2
2
1,900
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This post was last modified on 04 May 2020