Download OU B.Pharma 2-1 Year 2015 8038 S Pharmaceutical Organic Chemistry I Question Paper

Download OU (Osmania University) B.Pharma 2-1 (2nd Year 1st Sem) (Bachelor of Pharmacy) 2015 8038 S Pharmaceutical Organic Chemistry I Previous Question Paper

Pharmacy
Hyderabad
OU - 1701 OU - 1701
Code No. 8038 / S
FACULTY OF PHARMACY
B. Pharmacy 2/4 I-Semester (Supplementary) Examination, April 2015
Subject : Pharmaceutical Organic Chemistry - I
Time : 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 (a) Explain SP, SP
2
and SP
3
hybridizations with suitable examples. (8)
(b) Define the terms : (6)
(i) Dipole moment (ii) Bond angle
(iii) Molecular orbitals and give their significance in organic chemistry
OR
(c) Explain : (i) Inductive effect (ii) Enantiomerism and diastereomerism (8)
(iii) Resonance giving suitable examples
(d) Explain energy diagrams of reactants and products during the course of the
reaction. (6)
2 (a) Explain Markovnikovs and AntiMarkovnikovs addition with suitable examples. (7)
(b) Explain electrophilic addition in alkynes and conjugated dienes. (7)
OR
(c) Write a note an stereochemistry of cyclohexane. Write the structure of chair
conformation showing axial and equatorial bonds. (7)
(d) Explain Bayers strain theory. (7)
3 (a) Write any three general methods to prepare hydorxy (alcoholic) compounds. (4)
(b) Write mechanism, kinetics and stereochemistry involved in SN
1
and SN
2
reactions. (10)
OR
(c) Write mechanism involved in E
1
and E
2
eliminations. (5)
(d) explain Saytzeff rule and Hofmann rule. (5)
(e) Explain Williamsons synthesis of ethers. (4)
4 (a) Explain any four methods of preparation and reactivity of Carbonyl compounds. (7)
(b) Write any five important nucleophilic addition reactions which you have studied. (7)
OR
(c) Write any three general methods to prepare Carboxylic acids. (5)
(d) Explain why trichloroacetic acid is more acidic than dichloro and which in turn
more acidic than monochlorocetic acid. (4)
(e) Write two applications each for Diethylmalonate and Ethylacetoacetate. (5)
5 (a) Explain basicity in aliphatic and aromatic amines. (5)
(b) Write any three reactions of amines. (5)
(c) Write the Hinsbergs method of separation of amines. (4)
OR
(d) Write different methods of preparation of Nitro compounds. (7)
(e) Explain the different reactions and synthetic utility of aryl diazonium salts. (7)
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Pharmacy,Hyderabad
Pharmacy,Hyderabad
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