Download OU (Osmania University) B.Pharma 2-1 (2nd Year 1st Sem) (Bachelor of Pharmacy) 2010 7009 Pharmaceutical Analysis I (Chemical Analysis) Previous Question Paper
Code No. : 7009
FACULTY OF TECHNOLOGY
B. Pharmacy II Year I Semester (Suppl.)
Examination, June 2010
PHARMACEUTICAL ANALYSIS ?I
(Chemical Analysis)
Time: 3 Hours] [Max. Marks: 70
Note : Answer all questions. All questions carry equal marks.
1. a) i) What is a primary standard ? Explain briefly giving examples. 4
ii) Define the terms :
i) Ruggedness
ii) Precision
iii) Linearity
iv) Range
v) Error.
(2x5=10 Marks)
OR
b) i) What is meant by calibration and how do you calibrate the pipette ? 6
ii) Analyses of a sample of iron ore gave the following percentage values for the
iron content : 7.08, 7.21, 7.12, 7.09, 7.16, 7.14, 7.07, 7.14, 7.18, 7.11. Calculate
the mean and standard deviation for the values. 8
2. a) i) Write notes on the following :
A) Different concepts of Acidity and Basicity. 6
B) Neutralization indicators. 4
ii) The solubility product of silver chloride is 2.8x 10
-1?
mole/ Litt. Calculate
its solubility in g / Litre. 4
OR
(This paper contains 3 pages) 1 P.T.O.
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WHIN
Code No. : 7009
FACULTY OF TECHNOLOGY
B. Pharmacy II Year I Semester (Suppl.)
Examination, June 2010
PHARMACEUTICAL ANALYSIS ?I
(Chemical Analysis)
Time: 3 Hours] [Max. Marks: 70
Note : Answer all questions. All questions carry equal marks.
1. a) i) What is a primary standard ? Explain briefly giving examples. 4
ii) Define the terms :
i) Ruggedness
ii) Precision
iii) Linearity
iv) Range
v) Error.
(2x5=10 Marks)
OR
b) i) What is meant by calibration and how do you calibrate the pipette ? 6
ii) Analyses of a sample of iron ore gave the following percentage values for the
iron content : 7.08, 7.21, 7.12, 7.09, 7.16, 7.14, 7.07, 7.14, 7.18, 7.11. Calculate
the mean and standard deviation for the values. 8
2. a) i) Write notes on the following :
A) Different concepts of Acidity and Basicity. 6
B) Neutralization indicators. 4
ii) The solubility product of silver chloride is 2.8x 10
-1?
mole/ Litt. Calculate
its solubility in g / Litre. 4
OR
(This paper contains 3 pages) 1 P.T.O.
1 11111 11E11111 1111 1111 1111 Code No. :
b) i) Derive an equation to calculate the pH value of an aqueous solution of a salt
of weak base and strong acid. 6
ii) What are buffers ? How they are prepared ? Explain their mechanism of
action. Define buffer capacity. 8
3. a) i) Write notes on Redox indicators. 5
ii) Discuss in detail the different steps involved in a gravimetric analytical
technique with help of an example.
OR
b) i) Write notes on adsorption indicators. 6
ii) Explain Volhard's method for determination of chlorides. 8
4. a) i) Discuss the principle, procedure and apparatus used in the assay of oxygen. 7
ii) Write about different solvents and indicators used in Non-aqueous titrations.
7
OR
b) i) Discuss the principle and procedure for the assay of calcium gluconate. 7
ii) Discuss the principle of following : (4+3)
i) Potassium iodate titrations
ii) Argentometry titrations.
5. a) i) Calculate the volume of water to be added to 100 ml 72% sulphuric acid
(Specific gravity 1.63) to convert it into 26% acid. 4
ii) Calculate the molarity of sodium carbonate when 25 ml of it neutralises
30 ml of decimolar hydrochloric acid. 4
iii) Calculate the no. of moles of sodium hydroxide in 200 ml of 0.1 M sodium
hydroxide solution. 3
iv) 25.0 ml of Barium chloride was treated with excess of sulphuric acid. If the
weight of resultant Barium sulphate is 0.3298 g, Calculate the weight of Barium
chloride in the given solution (Ba = 137, Cl = 35.5, S = 32, 0 = 16). 3
OR
2
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WHIN
Code No. : 7009
FACULTY OF TECHNOLOGY
B. Pharmacy II Year I Semester (Suppl.)
Examination, June 2010
PHARMACEUTICAL ANALYSIS ?I
(Chemical Analysis)
Time: 3 Hours] [Max. Marks: 70
Note : Answer all questions. All questions carry equal marks.
1. a) i) What is a primary standard ? Explain briefly giving examples. 4
ii) Define the terms :
i) Ruggedness
ii) Precision
iii) Linearity
iv) Range
v) Error.
(2x5=10 Marks)
OR
b) i) What is meant by calibration and how do you calibrate the pipette ? 6
ii) Analyses of a sample of iron ore gave the following percentage values for the
iron content : 7.08, 7.21, 7.12, 7.09, 7.16, 7.14, 7.07, 7.14, 7.18, 7.11. Calculate
the mean and standard deviation for the values. 8
2. a) i) Write notes on the following :
A) Different concepts of Acidity and Basicity. 6
B) Neutralization indicators. 4
ii) The solubility product of silver chloride is 2.8x 10
-1?
mole/ Litt. Calculate
its solubility in g / Litre. 4
OR
(This paper contains 3 pages) 1 P.T.O.
1 11111 11E11111 1111 1111 1111 Code No. :
b) i) Derive an equation to calculate the pH value of an aqueous solution of a salt
of weak base and strong acid. 6
ii) What are buffers ? How they are prepared ? Explain their mechanism of
action. Define buffer capacity. 8
3. a) i) Write notes on Redox indicators. 5
ii) Discuss in detail the different steps involved in a gravimetric analytical
technique with help of an example.
OR
b) i) Write notes on adsorption indicators. 6
ii) Explain Volhard's method for determination of chlorides. 8
4. a) i) Discuss the principle, procedure and apparatus used in the assay of oxygen. 7
ii) Write about different solvents and indicators used in Non-aqueous titrations.
7
OR
b) i) Discuss the principle and procedure for the assay of calcium gluconate. 7
ii) Discuss the principle of following : (4+3)
i) Potassium iodate titrations
ii) Argentometry titrations.
5. a) i) Calculate the volume of water to be added to 100 ml 72% sulphuric acid
(Specific gravity 1.63) to convert it into 26% acid. 4
ii) Calculate the molarity of sodium carbonate when 25 ml of it neutralises
30 ml of decimolar hydrochloric acid. 4
iii) Calculate the no. of moles of sodium hydroxide in 200 ml of 0.1 M sodium
hydroxide solution. 3
iv) 25.0 ml of Barium chloride was treated with excess of sulphuric acid. If the
weight of resultant Barium sulphate is 0.3298 g, Calculate the weight of Barium
chloride in the given solution (Ba = 137, Cl = 35.5, S = 32, 0 = 16). 3
OR
2
111111111101 Code No. : 7009
b) i) Calculate the weight of Barium chloride required to produce 0.3 g of silver
chloride (Ba = 137, Ag = 108, Cl = 35.5). ? 3
ii) A sample containing 0.2 g of chloride gave 0.125 g precipitate of silver
chloride. Calculate the percent of chlorine in the sample. 5
iii) How many grams of sodium are contained in 25.0 g of sodium sulphate ?
(Na = 23, S = 32, 0 = 16). 2
iv) What is the empirical formula of an organic compound whose percentage
composition is ? 4
i) 29.8% C, 6.3% H, 44% Cl, 19.9% 0
ii) 48.7% C, 13.6% H, 37.8% N.
3 1,000
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This post was last modified on 04 May 2020