Download OU B.Pharma 3-1 Year 2013 2768 Medicinal Chemistry I Question Paper

Download OU (Osmania University) B.Pharma 3-1 (3rd Year 1st Sem) (Bachelor of Pharmacy) 2013 2768 Medicinal Chemistry I Previous Question Paper

PHARMACY
Code No. 2768
FACULTY OF PHARMACY
B. Pharmacy III-Year I-Semester (Supplementary) Examination, March / April
2013
Subject : Medicinal Chemistry - I
Time : 3 Hours Max. Marks: 70
Note: Answer All questions. All questions carry equal marks.
1.(a) Explain in detail the phase-I reactions of drug metabolism with examples. (7)
(b) Explain the role of prodrugs in drug design. (7)
OR
(c) Explain different physicochemical properties which influence biological
activity. (7)
(d) Write the importance of steric features of drugs. (7)
2.(a) What are adrenomimetics? Write SAR and uses of adrenergic drugs. (8)
(b) Classify parasympathomimetics with examples. (6)
OR
(c) Give the synthesis of (i) Atenolol (ii) Salbutamol. (8)
(d) Write the structures and uses of acetyl choline esterase inhibitors. (6)
3.(a) Give the classification of Antihypertensive drugs with structures and write the
synthesis of captopril and clonidine. (14)
OR
(b) Classify anitarrhythmic drugs with one suitable example for each class. (6)
(c) Write notes on antihyperlipidemic agents. (8)
4.(a) Define and classify diuretics with examples. (6)
(b) Write about hypoglycemic drugs. (8)
OR
(c) Write notes on Immunostimulants. (7)
(d) Give the synthesis of (7)
(i) Amilioride (ii) Glyclazide
5.(a) Write notes on proton pump inhibitors. (7)
(b) Explain in detail about anti-coagulation. (7)
OR
(c) Write the synthesis, M.O.A. of following drugs: (8)
(i) Citrazine (ii) Ranitidine
(d) Explain the SAR of H
1
antagonists. (6)
.
*****
FirstRanker.com - FirstRanker's Choice