Download OU B.Pharma 3-1 Year 2018 13043NON CBCS Medicinal Chemistry I Question Paper

Download OU (Osmania University) B.Pharma 3-1 (3rd Year 1st Sem) (Bachelor of Pharmacy) 2018 13043NON CBCS Medicinal Chemistry I Previous Question Paper

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Code No. 13043/Non CBCS
FACULTY
B. Pharmacy III/IV II?Semester (Non CBCS) (Backlo) Examination,
November 2018
Subject: Medicinal Chemistry I
Time: 3 Hrs Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1. a) Write the importance of steric features of drus 7
b) Explain the concept of pro and soft dru approach. 7
OR
c) Discuss in detail phase I reactions involved in the dru metabolism. 8
d) Explain abt (i) lipophilicity (ii) Solubility with examples 6
2. a) Write the pharmacoloical actions of Adrenaline and discuss the SAR of
adrenomimetics. 8
b) ive the structure and synthesis of followin 3+3
i) Salbutamol ii) Isoproterenol
OR
b) Write a notes on followin 7+7
i) Cholineric blockin aents
ii) Skeletal muscle relaxants
3. a) Define anti hypertensive and ive the classification with examples. 5
b) Write the SAR of ACE inhibitors. 5
c) ive the structure and synthesis of clofibrate. 4
OR
d) Adda note on Antiplatelet drus 7
e) Discuss abt cardiotonic aents 7
4. a) ive the classification of oral hypolycemic aents with examples. 4
b) Add a note on positive Inotrophic aents 6
c) ive the structure, uses and synthesis of Tolbutamide. 4
OR
d) Define and classify diurestics with examples. Write the MOA and SAR of carbonic
anhydrase inhibitors. 1+2+5
e) Add a note on Immuno suppressants. 6
Contd..2..
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.

Code No. 13043/Non CBCS
FACULTY
B. Pharmacy III/IV II?Semester (Non CBCS) (Backlo) Examination,
November 2018
Subject: Medicinal Chemistry I
Time: 3 Hrs Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1. a) Write the importance of steric features of drus 7
b) Explain the concept of pro and soft dru approach. 7
OR
c) Discuss in detail phase I reactions involved in the dru metabolism. 8
d) Explain abt (i) lipophilicity (ii) Solubility with examples 6
2. a) Write the pharmacoloical actions of Adrenaline and discuss the SAR of
adrenomimetics. 8
b) ive the structure and synthesis of followin 3+3
i) Salbutamol ii) Isoproterenol
OR
b) Write a notes on followin 7+7
i) Cholineric blockin aents
ii) Skeletal muscle relaxants
3. a) Define anti hypertensive and ive the classification with examples. 5
b) Write the SAR of ACE inhibitors. 5
c) ive the structure and synthesis of clofibrate. 4
OR
d) Adda note on Antiplatelet drus 7
e) Discuss abt cardiotonic aents 7
4. a) ive the classification of oral hypolycemic aents with examples. 4
b) Add a note on positive Inotrophic aents 6
c) ive the structure, uses and synthesis of Tolbutamide. 4
OR
d) Define and classify diurestics with examples. Write the MOA and SAR of carbonic
anhydrase inhibitors. 1+2+5
e) Add a note on Immuno suppressants. 6
Contd..2..
.

Code No. 13043/Non CBCS
2 5. a) Define and classify Anti histaminic aents with examples.
b) ive the SAR of any two classes of H1 Anti histaminic. 7
c) List t the coaulation factors. 4
OR
d) Write the structure, synthesis, MOA and uses of followin 5x4 = 14
i) Chlorpheniramine ii) Ranitidine
iii) Omeprazole iv) Warfarin
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