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GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm Practice- Year—I EXAMINATION — SUMMER -2018
Subject Code: rr101TP Date: 30/04/2018
Subject Name: PATHOPHYSIOLOGY & PHARMACOTHERAPEUTICS I
Time: 02:30 PM TO 05:30PM Total Marks: 60
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Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Discuss etiology, pathophysiology & treatment of Hypertension 06
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(b) Describe etiology & clinical manifestations of Heart failure 03(c) Explain pathophysiology of Hyperlipidemia 03
Q.2 (a) Discuss in detail treatment algorithm of Ischemic heart disease. 06
(b) Describe Pharmacotherapy of Atrial fibrillation. 03
(c) Discuss diagnostic tests of Hyperlipidemia 03
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Q.3 (a) Discuss diagnostic tests & clinical manifestations of Asthma 06
(b) What is Pathophysiology? Explain its scope in treatment of disease. 03
(c) Which factors should be considered in dose selection of a drug in a hepatically 03
challenged patient?
Q.4 (a) Discuss the role of pharmacokinetic factors in selection of a drug in pediatric 06
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population.(b) Explain etiology & pathophysiology of Torsade de Pointes 03
(c) Discuss pharmacotherapy of COPD 03
Q.5 (a) Enlist long term complications of Diabetes mellitus. Explain any two of them. 06
(b) Explain in detail pathophysiology of Asthma 03
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(c) Describe various forms of Congestive Heart Failure 03 Q.6 (a) Explain etiology, pathophysiology & Clinical manifestations of hypothyroidism 06
(b) Discuss GOLD classification of COPD. 03
(c) Give difference between Type 1 Diabetes mellitus & Type 2 Diabetes mellitus. 03
Q.7 (a) Describe etiology, diagnostic techniques & treatment of Grave’s disease 06
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(b) Discuss diagnostic techniques of Diabetes mellitus. 03(c) Explain step up & step down approach for treatment of asthma 03
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