Download GTU (Gujarat Technological University) B.Pharma (Bachelor of Pharmacy) 2018 Summer 2nf Sem 2220002 Pharmaceutical Chemistry Ii(Physical Chemistry) Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? II EXAMINATION ? SUMMER - 2018
Subject Code: 2220002
Date: 24/05/2018
Subject Name: Pharmaceutical Chemistry-II(Physical Chemistry)
Time: 10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
(a) Define: surface tension. Explain drop weight method for the determination of the 06
surface tension.
(b) Define viscosity & write units of it. Describe principle of Ostwald's viscometer.
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(c) Define: (i) Refractive index (ii) Parachor (iii) Specific rotation (iv) Optical
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activity (v) Dipole moment
Q.2
(a) State and explain Raoult's law of dilute solution. Discuss deviation of real
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solution from the Law.
(b) Define: Molarity and Normality. Explain Henry's law in brief.
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(c) Define colligative property. Enlist different types of colligative properties.
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Describe briefly lowering of the vapour pressure.
Q.3
(a) State and explain first Law of Thermodynamics.
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(b) State and explain phase rule. Describe phase diagram of water.
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(c) Define Thermodynamics. Write a detail note on Carnot cycle.
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Q.4
(a) What is an adsorption isotherm? Discuss in detail Langmuir adsorption isotherm. 06
(b) Enlist applications of adsorption. Describe in detail pharmaceutical application.
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(c) Differentiate: (1) Physical adsorption and Chemical adsorption.
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(2) Adsorption and Absorption
Q.5
(a) Derive the rate constant equation for first order reaction. Explain how to derive
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half-life equation for first order reaction.
(b) Define chemical kinetics. Discuss the methods of determination of order of a
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reaction.
(c) Paracetamol solution has initial concentration 500 mg/100 ml. After 40 days the
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concentration becomes 300 mg/100 ml. The reaction follows first order kinetic.
Calculate half-life and reaction rate constant.
Q. 6 (a) What is Photochemistry? Draw the Jablonski diagram & explain the
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consequences of light absorption.
(b) Define quantum yield of a photochemical reaction. Give reasons of high and low
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quantum yield.
(c) Explain the terms: (i) Photochemical reaction (ii) Photosensitiser
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(iii) Fluorescence (iv) Phosphorescence (v) Thermopile
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Q.7
(a) Differentiate the following pair:
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(1) Molecularity of a reaction & order of a reaction.
(2) Homocatalysis & Heterocatalysis.
(b) Explain the terms: (i) Adiabatic process (ii) Heat of Neutralization (iii) Entropy
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(iv) Heat of combustion (v) Joule-Thomson effect
(c) Define the term catalyst. Write a note on "Acid- Base and Enzyme catalysis".
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This post was last modified on 05 March 2021