GTU B.Pharma 2018 Summer Question Papers || Gujarat Technological University
Seat No.:
Subject Code: 2250003
--- Content provided by FirstRanker.com ---
Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER-5 * EXAMINATION - SUMMER -2018
Subject Name: Pharmaceutical Analysis 11T
Time: 02:30 PM TO 05:30 PM
--- Content provided by FirstRanker.com ---
Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) Derive Beer-Lambert’s law and explain various types of deviations from Beers Lambert’s law. (06)
- (b) Draw a labeled diagram of UV-Visible spectrophotometer. Explain various applications of UV- Visible spectrophotometry. (05)
- (a) One tablet of drug (mol. wt.: 250, e= 710) when dissolved and diluted to 2000 ml with water gave absorbance of 0.725 at 275 nm. Calculate mg of drug present in one tablet. (05)
- (b) Explain the effect of vibrational coupling, H-bonding and electronic factors on vibrational frequency in IR spectroscopy. (06)
- (c) Explain instrumentation of FTIR along with its advantages. (05)
- (a) Write a brief note on thermal detectors. (05)
- (b) Define chemical shift. Explain various factors affecting chemical shift. (06)
- (c) Explain theory and principle of NMR spectroscopy. (05)
- (a) Differentiate: (05)
- Proton and C13 NMR spectroscopy
- Fluorescence and Phosphorescence
- (b) Explain various factors affecting fluorescence intensity. (06)
- (c) Write a brief note on instrumentation of fluorimetry. (05)
- (a) Describe sample handling in IR spectroscopy. (05)
- (b) Explain various interferences in atomic absorption spectrophotometry and various approaches for its minimization. (06)
- (c) Write a brief note on photomultiplier tube. (05)
- (a) Explain different types of nebulizer burner system in flame photometry. (05)
- (b) Define: molecular ion, daughter ion, base ion and metastable ion. Explain in brief principle and application of mass spectroscopy. (06)
- (c) What is hard and soft source. Explain any one soft source in detail. (05)
- (a) What is resolution of mass analyzer. Explain briefly time of flight analyzer. (05)
- (b) Explain various rules for fragmentation in Mass spectroscopy. (06)
- (c) Define : Line spectra, Band spectra, wavelength, wave number, frequency How many numbers of signals and multiplets will appear for ethyl chloride and propyl bromide in Proton NMR spectroscopy? (05)
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Total Marks: 80
Date: 18/05/2018
--- Content provided by FirstRanker.com ---
This download link is referred from the post: GTU B.Pharma 2018 Summer Question Papers || Gujarat Technological University