Download GTU (Gujarat Technological University) B.Pharma (Bachelor of Pharmacy) 2018 Summer 6th Sem 2260002 Pharmaceutical Microbiology And Biotechnology Ii Previous Question Paper
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER?6 ? EXAMINATION ? SUMMER -2018
Subject Code: 2260002 Date: 05/05/2018
Subject Name: Pharmaceutical Microbiology & Biotechnology - II
Time: 10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Explain microbiological assay of Vitamin B12.
06
(b) Discuss the isolation & recovery of Fermentation products.
05
(c) Enlist methods for sterility testing. Discuss direct inoculation method.
05
Q.2 (a) Differentiate the sera and vaccines with examples.
06
(b) Write short notes on i) Streptokinase ii) Monoclonal antibodies
05
(c) Write in detail the fermentative productions of ethanol.
05
Q.3 (a) Describe the methods for Standardization & Screening of soil for organisms
06
producing antibiotics.
(b) Give the flow chart for the production of vitamin B12.
05
(c) What do you understand by the term mutagenesis? Explain Radiation as
05
Mutagen.
Q.4 (a) Describe scope of Biotechnology & its applications in pharmacy.
06
(b) Describe ideal characteristics of plasma substituent. Explain Dextran as a plasma
05
substituent.
(c) Write a note on mutation and its consequences.
05
Q.5 (a) Explain MoAb production and biochemical principle involved in hybrid selection.
06
(b) Write a note on recombinant DNA technology.
05
(c) Define Immunity and Classify it with examples.
05
Q. 6 (a) Write a note on protoplast Fusion.
06
(b) How is BCG vaccine prepared & sterilized?
05
(c) Why ELISA and Widal tests are performed? Explain the Tuberculin test.
05
Q.7 (a) Describe antigen-antibody reactions with examples.
06
(b) Sketch the flow diagrams for recovery & purification of streptomycin and
05
riboflavin from broth.
(c) Give short notes on Immunoglobulins.
05
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This post was last modified on 05 March 2021