Download GTU B.Pharma 2018 Summer 8th Sem 2280003 Semester 8 Question Paper

Download GTU (Gujarat Technological University) B.Pharma (Bachelor of Pharmacy) 2018 Summer 8th Sem 2280003 Semester 8 Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER?8 ? EXAMINATION ? SUMMER -2018

Subject Code: 2280003 Date: 02/05/2018
Subject Name: Pharmaceutical Chemistry ? X (Medicinal Chemistry - III)
Time: 10:30 AM TO 01:30 PM
Total Marks: 80

Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write a note on nomenclature and stereochemistry of steroids.
06

(b) Define and classify antidiabetic agents. Give the synthesis of tolbutamide.
05

(c) Write a note on anti-obesity drugs.
05



Q.2 (a) Give a detailed SAR of adreno-corticoids.
06

(b) Write a note on immunomodulators.
05

(c) Write a note on thrombolytic agents.
05



Q.3 (a) What are cardiotonic agents . Give SAR of cardiac glycosides.
06

(b) Define and classify antianginal agents. Give synthesis of glyceryltrinitrate.
05

(c) Write a note on antiplatelet agents.
05



Q.4 (a) Define and classify antihypertensive agents. Give synthesis of atenolol.
06

(b) Write a note on coagulants and anticoagulants.
05

(c) Write a note on antithyroid drugs.
05



Q.5 (a) Give a detailed SAR on progestins and androgens.
06

(b) Give synthesis of methimazole and carbimazole.
05

(c) Write a note on antihyperlipidemic agents.
05



Q. 6 (a) Give the IUPAC name and synthesis of 1)lignocaine 2) clofibrate 3) warfarin
06

(b) Write a note on plasma expanders.
05

(c) Write a note on thyroid hormones.
05



Q.7 (a) What are diuretics. Give detailed SAR of thiazide diuretics.
06

(b) Give synthesis of hydrochlorthiazide and Furosemide.
05

(c) Give synthesis of metformin and pioglitazone.
05
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